Stokes位移光谱在生物医学应用和生物制剂传感中的应用

A. Katz, R. Alfano
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引用次数: 0

摘要

斯托克斯位移光谱(Sss)是一种结合激发和发射光谱的技术,以增强识别荧光特征的能力,当几个生物分子具有重叠的光谱存在。Sss提供了一种改进的方法来测量具有宽发射波段的荧光团在大噪声水平下的光谱指纹图谱。在这项工作中,Sss技术被用于两种不同的应用:组织中恶性肿瘤的检测,以及生物制剂(细菌和病毒)的原位传感和监测。
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Stokes shift spectroscopy for biomedical applications and bio-agent sensing
Stokes shift Spectroscopy (Sss) is a technique that combines excitation and emission spectroscopy to enhance the ability to identify fluorescence signatures when several biomolecules with overlapping spectra are present. Sss provides an improved method to measure the spectral fingerprints of fluorophores with broad emission bands in situations with large noise levels. In this work, the Sss technique was used in two different applications the detection of malignancy in tissues, and in situ sensing and monitoring of bio-agents (bacteria and viruses).
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