实验室服务在及时评估甲状腺结节患者危险因素中的作用,作为预防术后并发症的工具

O. I. Zalyubovska, N. О. Hladkykh, M. Polion
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引用次数: 0

摘要

目的:探讨实验室一次性检测甲状腺激素危险因素的方法。材料与方法:检查包括问卷调查、超声细针穿刺检查(FNA)、细胞学检查、甲状腺激素浓度测定和体质指数测定。结果与结论:根据超声判断肿瘤的大小和面积(H = 2.30, p> 0.05; H = 1.92, p> 0.05)。同时,与其他组患者相比,第一组患者年龄小于(时)。良性甲状腺肿瘤(I组)的特点是:66.7%的患者血清游离甲状腺素(FT4)水平不超过正常,平均为14.0 (8.0-16.29)pmol/l。疑似恶性肿瘤组:血清FT4浓度极低(1.94 (1.44-7.00)pmol/l);40.0%的病例有高水平的FT3产量,平均值移至参考区间的上限。恶性甲状腺肿瘤(III组)患者的甲状腺状况以TSH水平高于良性肿瘤(p <0.05)和疑似恶性肿瘤(p <0.1)为特征。血清中FT4的产生显著降低(比良性病程低7.4倍);p <0.001),背景是FT3的平均调控水平。
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The Role of the Laboratory Service in the Timely Assessment Of Risk Factors in Patients with Thyroid Nodules as a Tool to Prevent Postoperative Complications
Aim: To study of thyroid hormones with one-time determination of risk factors in the laboratory. Material and methods: The examination included the following researches: questionnaire, ultrasound examination with fine-needle aspiration (FNA), cytological examination, determination of the concentration of thyroid hormones and determining the body mass index. Results and conclusions: the size and area of the tumor according to ultrasound (H = 2.30, p> 0.05 and H = 1.92, p> 0.05, respectively). At the same time, patients of the 1st group were younger in age than (when) compared with patients of other groups. For benign thyroid tumors (group I) are characterized by the following data: the level of free thyroxine (FT4) in the serum of 66.7% of patients did not exceed normal and averaged 14.0 (8.0-16.29) pmol/l. Group with suspected tumor malignancy include: very low concentration of FT4 in serum (1.94 (1.44-7.00) pmol/l); high level of FT3 production in 40.0% of cases with a shift of the mean values to the upper limit of the reference interval. Thyroid status of patients with malignant thyroid tumors (group III) is characterized by elevated levels of TSH compared with benign tumors (p <0.05) and suspected malignancy of the tumor (p <0.1). A significant decrease in the production of FT4 in the serum (7.4 times compared with the benign course; p <0.001) against the background of average regulatory levels of FT3.
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