非侵入式传感器贴片的压阻聚合物痕迹评价

Ramona B. Damalerio, Ruiqi Lim, Weiguo Chen, D. Choong, Ming-Yuan Cheng
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引用次数: 2

摘要

在本文中,我们将讨论合适的替代材料,以创造无创柔性传感器贴片的痕迹或电极,用于检测静脉插管期间的早期外渗。样品是通过在基聚合物贴片上印刷5 \mu \ mathm {m} -$至10 \mu \ mathm {m} -$薄的压阻性聚合物基碳糊来制备的,也称为粘接膜。第一个样品的痕迹嵌入在两个基材胶膜之间。样品的灵敏度是通过使用带有4厘米孔的压力室/夹具来模拟当与15 psi源连接的压缩干空气(CDA)泵送时由凸起形成的外溢来表征的。在0.16 psi下获得的灵敏度值为20%至23%。在优化了胶膜和压阻性聚合物碳迹固化温度后,将原型样品放置在猪前飞节穿刺部位进行离体试验。在输注2 ml和5 ml液体时,灵敏度分别仅为1.1%和2.44%。所有样品的整体原型尺寸为6 × 7 cm2。制备的第二种样品比第一种样品的迹线宽度和间距更窄。在0.16 psi下从第二个样品获得的灵敏度增加到50%到79%。第三个样品与第二个样品具有相同的窄迹,但这一次压阻性聚合物基迹没有嵌入两个胶膜中,使样品仅为单层贴片。在0.16 psi下获得的灵敏度进一步增加到140%至200%。0.16 psi的读数是基于之前的数据,在这个压力下,在4毫米的孔中产生粘胶膜,在2ml的注入量下,它在皮肤上转化为3毫米的凸起高度。研究结果表明,压阻性聚合物基碳迹在开发用于早期外渗检测的柔性无创传感器贴片方面具有很大的潜力。
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Evaluation of Piezoresistive Polymer-based Traces for Non-invasive Sensor Patch
In this paper, we shall discuss the suitable alternative material to gold for creating traces or electrodes of a noninvasive flexible sensor patch that is used for detecting early extravasation during intravenous cannulation. The samples were prepared by printing $5 \mu \mathrm{m} -$ to $10 \mu \mathrm{m} -$ thin piezoresistive polymer-based Carbon paste on a base polymer patch, also called the adhesive film. The first samples have the traces embedded in between two base adhesive films. The sensitivity of the samples was characterized by using a pressure chamber/jig with 4 cm hole to mimic an extravasation by bump formation when pumped with compressed dry air (CDA) that is connected to a 15 psi source. The sensitivity value obtained was 20% up to 23% at 0.16 psi. After optimization of the curing temperature of the adhesive film and piezoresistive polymer-based Carbon traces, ex-vivo test was conducted with the prototype sample placed on the cannulation site of a pork front hock. At 2 ml and 5 ml infused fluid, the sensitivity obtained is only 1.1% and 2.44%, respectively. The overall prototype dimension of all samples is 6 × 7 cm2. The second samples were prepared with narrower trace width and spacing than the first samples. Sensitivity obtained from the second sample at 0.16 psi increased to 50% up to 79%. The third samples were prepared with the same narrow trace with as the second sample, but this time the piezoresistive polymer-based traces were not embedded in two adhesive films, making the sample a single layer patch only. Sensitivity obtained at 0.16 psi increased further to 140% up to 200%. The 0.16 psi readout is based on previous data that at this pressure induced in the 4 mm hole where the adhesive film is placed over, it translates to 3mm bump height at 2ml infused volume on the skin. The results suggest a strong potential in the development of the piezoresistive polymer-based Carbon traces for flexible non-invasive sensor patch for early extravasation detection.
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