{"title":"从药代动力学到细胞内动力学阶段;纳米颗粒直接导入活细胞细胞质的研究","authors":"T. Mayumi","doi":"10.1109/ICMENS.2004.73","DOIUrl":null,"url":null,"abstract":"We developed a technology to directly introduce nanoparticles into the cytoplasm of living cells at one time without using a micromanipulator. Moreover, we confirmed that antisense oligonucleotides as a model drug can be released slowly in cytoplasm from these particles.","PeriodicalId":344661,"journal":{"name":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2004-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"From the Pharmacokinetics to the Intracellular Dynamic Phase — Direct Introduction of Nanoparticles into Cytoplasm of Living Cells\",\"authors\":\"T. Mayumi\",\"doi\":\"10.1109/ICMENS.2004.73\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We developed a technology to directly introduce nanoparticles into the cytoplasm of living cells at one time without using a micromanipulator. Moreover, we confirmed that antisense oligonucleotides as a model drug can be released slowly in cytoplasm from these particles.\",\"PeriodicalId\":344661,\"journal\":{\"name\":\"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)\",\"volume\":\"22 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2004-08-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICMENS.2004.73\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICMENS.2004.73","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
From the Pharmacokinetics to the Intracellular Dynamic Phase — Direct Introduction of Nanoparticles into Cytoplasm of Living Cells
We developed a technology to directly introduce nanoparticles into the cytoplasm of living cells at one time without using a micromanipulator. Moreover, we confirmed that antisense oligonucleotides as a model drug can be released slowly in cytoplasm from these particles.
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