流感嗜血杆菌DNA的宿主特异性:Rd菌株DNA限制性修饰不稳定性的生理和遗传基础。

A Piekarowicz, J Baj
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引用次数: 0

摘要

进一步研究了流感嗜血杆菌Rd菌株限制性修饰特性的不稳定性。研究表明,hsd Hind1系统的不稳定性即使在转移到另一株流感嗜血杆菌后仍保持不变。hsd Hind1系统的表达对各种生理变化非常敏感,这些生理变化不影响同一品系中存在的其他hsd系统。hsd Hind1系统的不稳定性与某些调控基因有关。
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Host specificity of DNA in haemophilus influenzae: The physiological and genetical bases of instability of restriction and modification of DNA in strain Rd.

Further investigations of the instability of restriction and modification properties of H. influenzae Rd strain were carried out. It has been shown that the instable properties of hsd Hind1 system are maintained even after transfer of this system to another H. influenzae strain. The expression of hsd Hind1 system is very sensitive to various physiological changes which do not influence the other hsd systems present in the same Rd strain. The instability of hsd Hind1 system is postulated to be connected with some regulator gene(s).

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