噬菌体在大肠杆菌小细胞上吸附后的核糖核酸合成。

H Witkiewicz, K Taylor
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引用次数: 0

摘要

λ噬菌体吸附在大肠杆菌P678-54异常细胞分裂产生的无染色体小体(微细胞)上。无质粒的小细胞,以及携带大肠杆菌致病因子E1的小细胞,在噬菌体吸附后显示出对总RNA合成的相当大的抑制作用。这两种小细胞都能合成与DNA杂交的RNA,但在含有小细胞的质粒中,RNA的合成更为密集。
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Ribonucleic acid synthesis after adsorption of the bacteriophage lambda on Escherichia coli minicells.

Lambda bacteriophage adsorbs on the chromosome-less small bodies (minicells) produced by aberrant cell division of Escherichia coli P678-54. The plasmid-less minicells, as well as the minicells harbouring the colicinogenic factor E1, reveal a considerable inhibition of total RNA synthesis after phage adsorption. Both kinds of minicells synthesize RNA hybridizable to lambda DNA, but in the plasmid-harbouring minicells lambda RNA synthesis is much more intensive.

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