Xin Zhu, Xiaowei Wang, Z. Cao, Zhi Ye, Chaoming Gu, Chuanghong Jin, Yang Liu
{"title":"结合ITO电极的纳米孔用于DNA在不同折叠状态下的电门控","authors":"Xin Zhu, Xiaowei Wang, Z. Cao, Zhi Ye, Chaoming Gu, Chuanghong Jin, Yang Liu","doi":"10.1109/IEDM.2017.8268466","DOIUrl":null,"url":null,"abstract":"Nanopore devices integrated with ITO gate electrodes are fabricated, producing pore diameters <10nm and lengths ∼30nm. Translocation signals of λ-DNA reveal detailed signatures of various DNA folding states. The gate bias V<inf>G</inf> modulates the translocation events. As V<inf>G</inf> rises from −0.5V to 0.5V, the count of folded-once events increases by ∼5.5X relative to that of unfolded ones, indicating capability of electrically modulating the effective pore cross-section.","PeriodicalId":412333,"journal":{"name":"2017 IEEE International Electron Devices Meeting (IEDM)","volume":"46 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Nanopores incorporating ITO electrodes for electrical gating of DNA at different folding states\",\"authors\":\"Xin Zhu, Xiaowei Wang, Z. Cao, Zhi Ye, Chaoming Gu, Chuanghong Jin, Yang Liu\",\"doi\":\"10.1109/IEDM.2017.8268466\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Nanopore devices integrated with ITO gate electrodes are fabricated, producing pore diameters <10nm and lengths ∼30nm. Translocation signals of λ-DNA reveal detailed signatures of various DNA folding states. The gate bias V<inf>G</inf> modulates the translocation events. As V<inf>G</inf> rises from −0.5V to 0.5V, the count of folded-once events increases by ∼5.5X relative to that of unfolded ones, indicating capability of electrically modulating the effective pore cross-section.\",\"PeriodicalId\":412333,\"journal\":{\"name\":\"2017 IEEE International Electron Devices Meeting (IEDM)\",\"volume\":\"46 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2017 IEEE International Electron Devices Meeting (IEDM)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/IEDM.2017.8268466\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2017 IEEE International Electron Devices Meeting (IEDM)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IEDM.2017.8268466","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Nanopores incorporating ITO electrodes for electrical gating of DNA at different folding states
Nanopore devices integrated with ITO gate electrodes are fabricated, producing pore diameters <10nm and lengths ∼30nm. Translocation signals of λ-DNA reveal detailed signatures of various DNA folding states. The gate bias VG modulates the translocation events. As VG rises from −0.5V to 0.5V, the count of folded-once events increases by ∼5.5X relative to that of unfolded ones, indicating capability of electrically modulating the effective pore cross-section.