Loin pain hematuria syndrome – A case report of a challenging diagnosis for clinicians

Loin pain hematuria syndrome (LPHS) is a rare syndrome of loin pain associated with hematuria, which could be either gross or microscopic in nature. The condition causes severe discomfort for patients and can lead to many limitations in activities of daily life. As such, no primary kidney pathology has been associated with this syndrome which makes it a unique entity, to be diagnosed after exclusion of secondary causes of these symptoms. The symptom complex of Loin pain hematuria has been described classically presenting in young females in their third decade and is known to have spontaneous remissions in almost half of the patients, while as rest of the patients continue to have recurrent episodes of pain and hematuria. A high index of suspicion needs to be developed by treating physician in a patient with recurrent loin pain associated with/out hematuria. We present a patient with a similar clinical course where the diagnosis of LPHS was made on clinical grounds after excluding secondary causes of her symptoms.