65岁以上内分泌科门诊患者用药评价

Sinem Gürcü, A. Kalkan
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摘要

目的:多种药物使用对个人和卫生系统都造成负担。这在老年患者群体中经常观察到。为了预防多药,已经开发了各种量表。我们的目的是应用比尔斯标准用于这一目的的处方患者谁申请内分泌门诊诊所。方法:选取102例65岁及以上在内分泌科门诊进行常规对照且处方中至少有4种药物的患者作为研究对象。对患者的人口统计资料和用药情况进行记录和评价。结果:纳入研究的102例患者中,70例(68.6%)为女性。83例(81.4%)慢性病理以糖尿病为主。用药不当以内分泌系统类药物最为常见。按照2019年Beers标准对纳入研究的处方进行回顾性评价,发现42张处方(41.2%)存在用药不当。结论:考虑到药物的药效学和药代动力学特性随年龄的变化而变化,多重用药和不当用药的重要性已经显现出来,并建立了标准化的量表来评价老年患者的这种情况。在这项研究中,胰岛素、质子泵抑制剂和非甾体抗炎药似乎是最常见的不合适的药物。应用比尔斯标准,其中一种多药量表可能是合理有效治疗老年人的正确方法。
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Evaluation of drug use in patients over 65 years of age admitted to endocrinology outpatient clinic with beers criteria
Aims: Multiple drug use creates a burden on both the individual and the health system. And this is often observed in advanced age patient groups. Various scales have been developed for the prevention of polypharmacy. We aimed to apply the Beers criteria used for this purpose in the prescriptions of patients who applied to the endocrinology outpatient clinic. Methods: 102 patients aged 65 years and over who applied to the endocrinology outpatient clinic for routine control and who had at least four drugs in their prescription were included in this study. Demographic data and drug use status of the patients were recorded and evaluated. Results: Of the 102 cases included in the study, 70 (68.6%) were women. The most common chronic pathology was diabetes mellitus in 83 (81.4%) cases. Inappropriate drug use was most common in endocrine system drugs. The prescriptions included in the study were evaluated according to the 2019 Beers criteria retrospectively and inappropriate drug use was detected in 42 prescriptions (41.2%). Conclusion: Considering the pharmacodynamic and pharmacokinetic properties of drugs that change with age, the importance of polypharmacy and inappropriate drug use has emerged, and standardized scales have been created to evaluate this situation in elderly patients. In this study, insulins, proton pump inhibitors, and non-steroidal anti-inflammatory drugs seem to be the most commonly administered inappropriate drugs. Applying Beers criteria, one of the polypharmacy scales may be the right approach for a rational and effective treatment in the elderly.
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