Ola Abuzaid, Şefika Akyol, Said Can Alcalı, Ekrem Ünal
{"title":"噬血细胞淋巴组织细胞增多症:给细胞因子风暴浇上汽油","authors":"Ola Abuzaid, Şefika Akyol, Said Can Alcalı, Ekrem Ünal","doi":"10.51271/kmj-0036","DOIUrl":null,"url":null,"abstract":"Hemophagocytic lymphohistiocytosis should be considered in patients with persistent fever, hepatosplenomegaly, pancytopenia. Hypercytokinemia originated from genetic disorder effecting the cellular defects of cytotoxic T and natural killer lymphocyte activity is the underlying pathophysiology of the disorder. In this review we summarized the recent advances in the management of hemophagocytic lymphohistiocytosis.","PeriodicalId":369732,"journal":{"name":"Kastamonu Medical Journal","volume":"38 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hemophagocytic lymphohistiocytosis: pouring gasoline on the cytokine storm\",\"authors\":\"Ola Abuzaid, Şefika Akyol, Said Can Alcalı, Ekrem Ünal\",\"doi\":\"10.51271/kmj-0036\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hemophagocytic lymphohistiocytosis should be considered in patients with persistent fever, hepatosplenomegaly, pancytopenia. Hypercytokinemia originated from genetic disorder effecting the cellular defects of cytotoxic T and natural killer lymphocyte activity is the underlying pathophysiology of the disorder. In this review we summarized the recent advances in the management of hemophagocytic lymphohistiocytosis.\",\"PeriodicalId\":369732,\"journal\":{\"name\":\"Kastamonu Medical Journal\",\"volume\":\"38 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-06-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Kastamonu Medical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.51271/kmj-0036\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Kastamonu Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.51271/kmj-0036","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hemophagocytic lymphohistiocytosis: pouring gasoline on the cytokine storm
Hemophagocytic lymphohistiocytosis should be considered in patients with persistent fever, hepatosplenomegaly, pancytopenia. Hypercytokinemia originated from genetic disorder effecting the cellular defects of cytotoxic T and natural killer lymphocyte activity is the underlying pathophysiology of the disorder. In this review we summarized the recent advances in the management of hemophagocytic lymphohistiocytosis.
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