麻疯树抗病毒活性研究进展

A. Utshudi, R. O. Oleko, C. Kayembe, D. Onautshu, E. M. Kitete, B. M. Mbala, P. Mpiana
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引用次数: 0

摘要

背景:麻疯树因其具有抗病毒、抗真菌和抗菌等多种生物活性而闻名。目的:为一些具有药用价值的麻疯树的植物化学、毒理学和抗病毒活性提供最新的认识。研究设计:多学科的高级书目调查和结果知识的传播。结果:文献综述表明麻疯树对不同类型的病毒具有抗病毒作用。据报道,这种植物的不同部位,如叶子、根、乳胶、种子、果实和其他部位含有不同的化合物,这些化合物具有有趣的生物活性和抗病毒特性。结论:本综述可以为今后的科学研究提供参考,以开发抗乙型肝炎病毒和抗新冠病毒的相关草药,以及利用反向药理学方法开发蓖麻植物营养保健品,以改善人类健康和福祉。一些天然存在的抗乙型肝炎病毒蛋白酶分离化合物的分子对接正在进行中。
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Antiviral Activities of Jatropha curcas: A Review
Background: The Plant of Jatropha curcas is known for their many biological activities including antiviral, antifungal and antibacterial. Aim: To provide update knowledge on the phytochemistry, toxicology and antiviral activity of some medically interesting Jatropha curcas. Study Design: Multidisciplinary advanced bibliographic surveys and dissemination of the resulted knowledge. Results: The literature review shows that Jatropha curcas have antiviral properties on different types of viruses. Different parts of the plant such as leaves, roots, latex, seeds, fruits and other parts have been reported to have different compounds which have interesting bioactivities and antiviral properties. Conclusion: The present mini-review can therefore help inform future scientific research towards the development of anti-Hepatitis B virus and antiCovid-19 herbal drugs of relevance as well as nutraceuticals from J. curcas for the improvement of human health and wellbeing using reverse pharmacology approach. Molecular docking of some naturally occurring isolate compounds against anti-Hepatitis B virus protease is in progress.
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