{"title":"人胚肺异倍体细胞PZH-1细胞系生物学特性的研究。","authors":"I Polna, J Starzyńska","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The morphological and karyological properties as well as susceptibility to virus strain of tissue culture derived from human embryo lung that underwent a transformation becoming a continuous line defined as PZH-1 were observed. The observations cover 120 passages divided into four phases: one before and three after transformation. Each of these phases was characterised by different biological strain properties. Loss of PZH-1 susceptibility to ECHO virus was the first change of biological properties preceding in time changes in growth rate, cell morphology and chromosome complement. The loss of susceptibility to ECHO virus may indicate cell transformation.</p>","PeriodicalId":75389,"journal":{"name":"Acta microbiologica Polonica. Series A: Microbiologia generalis","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Studies on some biological properties of heteroploidal cell -- PZH-1 line derived from human embryo lung.\",\"authors\":\"I Polna, J Starzyńska\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The morphological and karyological properties as well as susceptibility to virus strain of tissue culture derived from human embryo lung that underwent a transformation becoming a continuous line defined as PZH-1 were observed. The observations cover 120 passages divided into four phases: one before and three after transformation. Each of these phases was characterised by different biological strain properties. Loss of PZH-1 susceptibility to ECHO virus was the first change of biological properties preceding in time changes in growth rate, cell morphology and chromosome complement. The loss of susceptibility to ECHO virus may indicate cell transformation.</p>\",\"PeriodicalId\":75389,\"journal\":{\"name\":\"Acta microbiologica Polonica. Series A: Microbiologia generalis\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1975-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta microbiologica Polonica. Series A: Microbiologia generalis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta microbiologica Polonica. Series A: Microbiologia generalis","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Studies on some biological properties of heteroploidal cell -- PZH-1 line derived from human embryo lung.
The morphological and karyological properties as well as susceptibility to virus strain of tissue culture derived from human embryo lung that underwent a transformation becoming a continuous line defined as PZH-1 were observed. The observations cover 120 passages divided into four phases: one before and three after transformation. Each of these phases was characterised by different biological strain properties. Loss of PZH-1 susceptibility to ECHO virus was the first change of biological properties preceding in time changes in growth rate, cell morphology and chromosome complement. The loss of susceptibility to ECHO virus may indicate cell transformation.
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