PPHN右至左导管分流与导管前后血氧饱和度差异-并非完全相关?

Amy L. Lesneski, Morgan E Hardie, Payam Vali, S. Lakshminrusimha
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摘要

背景:新生儿持续性肺动脉高压(PPHN)通常继发于肺部疾病,如胎粪吸入综合征(MAS),其特征是肺外卵圆孔右向左或双向分流和/或动脉导管未闭(PDA)。在PDA处分流导致传导后区域的氧饱和度(SaO2)和PaO2降低。然而,研究并没有直接评估同时发生的导管前后血气和导管分流的方向。目的:评价……
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Right-to-Left Ductal Shunting and Preductal and Postductal Oxygen Saturation Difference in PPHN- Not a Perfect Correlation?
Background: Persisent pulmonary hypertension of the newborn (PPHN) is often secondary to lung disease such as meconium aspiration syndrome (MAS) and is characterized by extrapulmonary right-to-left or bidirectional shunting at the foramen ovale and/or patent ductus arteriosus (PDA). Shunting at the PDA results in reduced oxygen saturation (SaO2) and PaO2 in the postductual region. However, studies have not directly evaluated simultaneous preductal and postductal blood gases and direction of ductal shunt. Objective: To evaluate …
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