Pub Date : 2021-02-24DOI: 10.1542/PEDS.147.3_MEETINGABSTRACT.712
A. Damianos, Pingpin Chen, Shathiyah Kulandavelu, Mayank Sharma, Jian Huang, Sunil Batlahally, Ronald Zambrano, Shaoyi Chen, A. Scmidt, Shu Wu, N. Claure, M. Benny, K. Young
{"title":"Long-term Cardiopulmonary Effects of Neonatal Intermittent Hypoxia Exposure","authors":"A. Damianos, Pingpin Chen, Shathiyah Kulandavelu, Mayank Sharma, Jian Huang, Sunil Batlahally, Ronald Zambrano, Shaoyi Chen, A. Scmidt, Shu Wu, N. Claure, M. Benny, K. Young","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.712","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.712","url":null,"abstract":"","PeriodicalId":275302,"journal":{"name":"Section on Neonatal-Perinatal Medicine Program","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127201387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-24DOI: 10.1542/PEDS.147.3_MEETINGABSTRACT.680
M. Barbian, Joshua A. Owens, P. Denning, R. Patel, Rheinallt M. Jones
{"title":"Antenatal Dietary Butyrate Supplementation Reduces Postnatal Gastrointestinal Injury in a Murine Model of Colitis","authors":"M. Barbian, Joshua A. Owens, P. Denning, R. Patel, Rheinallt M. Jones","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.680","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.680","url":null,"abstract":"","PeriodicalId":275302,"journal":{"name":"Section on Neonatal-Perinatal Medicine Program","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133527573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-24DOI: 10.1542/PEDS.147.3_MEETINGABSTRACT.708
H. French, Msed, Allison H. Payne, Eric Zucker, H. Karpen, Melissa M. Carbajal, AnnaMarie Arias-Shah, R. Dadiz, L. Johnston, M. Gillam-Krakauer, S. Izatt, Margarita M. Vasquez, Carly Gisondo, Alison J Falck, E. Bonachea, P. Chess, M. Gray
{"title":"Impact of Instructional Method on Perceptions of the Learning Environment","authors":"H. French, Msed, Allison H. Payne, Eric Zucker, H. Karpen, Melissa M. Carbajal, AnnaMarie Arias-Shah, R. Dadiz, L. Johnston, M. Gillam-Krakauer, S. Izatt, Margarita M. Vasquez, Carly Gisondo, Alison J Falck, E. Bonachea, P. Chess, M. Gray","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.708","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.708","url":null,"abstract":"","PeriodicalId":275302,"journal":{"name":"Section on Neonatal-Perinatal Medicine Program","volume":"168 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133225593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-24DOI: 10.1542/PEDS.147.3_MEETINGABSTRACT.719
Diksha Shrestha, G. Ye, D. Stabley, Suhita Gayen Nee'Betal, Yan Zhu, L. Glazewski, J. Holbrook, T. Shaffer, Z. Aghai, S. Addya, D. Alapati
{"title":"Perinatal lung inflammation in a double-hit model of bronchopulmonary dysplasia results in short-term and long-term downregulation of pulmonary T cell receptor signaling","authors":"Diksha Shrestha, G. Ye, D. Stabley, Suhita Gayen Nee'Betal, Yan Zhu, L. Glazewski, J. Holbrook, T. Shaffer, Z. Aghai, S. Addya, D. Alapati","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.719","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.719","url":null,"abstract":"","PeriodicalId":275302,"journal":{"name":"Section on Neonatal-Perinatal Medicine Program","volume":"42 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117245239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-24DOI: 10.1542/PEDS.147.3_MEETINGABSTRACT.678
Z. Begun, A. Kushnir, Evan Graber
Introduction: Diazoxide is the first-line treatment used to manage infants and children with hypoglycemia secondary to hyperinsulinemic hypoglycemia (HH), after initial stabilization of blood glucose. Recent changes in Pediatric Endocrine Society guidelines regarding definition of, and screening for hypoglycemia in the neonate led to an increase in the number of infants treated with diazoxide. Previous studies have noted various side effects of diazoxide. With the increased use of this drug in neonates, our aim is to further evaluate these side effects. Methods: We performed a retrospective case control analysis of all neonates admitted to a tertiary care center in New Jersey who were treated with diazoxide for hypoglycemia after a confirmed diagnosis of HH between 1/1/2015 and 9/1/2019. All subjects were younger than 6 months of age at treatment initiation with diazoxide. We collected data regarding general patient characteristics, diuretic dosing, findings on echocardiogram, blood counts, episodes of emesis, and quantity of feeds at time points before and after diazoxide initiation. Results: A total of 25 infants (64% males) met inclusion criteria and were included in the analysis. Based on echocardiogram results, one baby (4%) had pulmonary hypertension (PHTN) prior to initiation of diazoxide, and 20% after, with 5 cases (20%) of reopening of the ductus arteriosus (DA). Nine patients (36%) required a diuretic dose increase after diazoxide initiation. There was increased feeding intolerance with increased number of emesis events after diazoxide initiation (p=0.006). A week after initiation of diazoxide, there was no improvement in the percent of total oral intake as would typically be expected. Conclusion: New onset PHTN and re-opening of the DA were associated
{"title":"Adverse Effects Associated with Diazoxide Use in Neonates","authors":"Z. Begun, A. Kushnir, Evan Graber","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.678","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.678","url":null,"abstract":"Introduction: Diazoxide is the first-line treatment used to manage infants and children with hypoglycemia secondary to hyperinsulinemic hypoglycemia (HH), after initial stabilization of blood glucose. Recent changes in Pediatric Endocrine Society guidelines regarding definition of, and screening for hypoglycemia in the neonate led to an increase in the number of infants treated with diazoxide. Previous studies have noted various side effects of diazoxide. With the increased use of this drug in neonates, our aim is to further evaluate these side effects. Methods: We performed a retrospective case control analysis of all neonates admitted to a tertiary care center in New Jersey who were treated with diazoxide for hypoglycemia after a confirmed diagnosis of HH between 1/1/2015 and 9/1/2019. All subjects were younger than 6 months of age at treatment initiation with diazoxide. We collected data regarding general patient characteristics, diuretic dosing, findings on echocardiogram, blood counts, episodes of emesis, and quantity of feeds at time points before and after diazoxide initiation. Results: A total of 25 infants (64% males) met inclusion criteria and were included in the analysis. Based on echocardiogram results, one baby (4%) had pulmonary hypertension (PHTN) prior to initiation of diazoxide, and 20% after, with 5 cases (20%) of reopening of the ductus arteriosus (DA). Nine patients (36%) required a diuretic dose increase after diazoxide initiation. There was increased feeding intolerance with increased number of emesis events after diazoxide initiation (p=0.006). A week after initiation of diazoxide, there was no improvement in the percent of total oral intake as would typically be expected. Conclusion: New onset PHTN and re-opening of the DA were associated","PeriodicalId":275302,"journal":{"name":"Section on Neonatal-Perinatal Medicine Program","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125030775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-24DOI: 10.1542/PEDS.147.3_MEETINGABSTRACT.739
Vanessa Bray, Jean Lim, Miriam Aguilar-Lopez, S. Donovan, M. Groer, C. Wetzel, Thao T. B. Ho
Purpose: The gut microbiome is the totality of microorganisms present in the gastrointestinal tract. Gut microbial development in preterm infants is affected by environmental and genetic factors; however, the extent to which these factors play a role in shaping the preterm infant gut microbiome is poorly understood. Studying the gut microbiome of multiplets (twins and triplets) in relation to their environmental exposures, such as enteral feeding type, can provide insight into genetic versus environmental influences on the gut microbiome. We aimed …
{"title":"The Developing Microbiome in Preterm Multiplets vs Singletons- A Prospective Two-center Observational Study","authors":"Vanessa Bray, Jean Lim, Miriam Aguilar-Lopez, S. Donovan, M. Groer, C. Wetzel, Thao T. B. Ho","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.739","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.739","url":null,"abstract":"Purpose: The gut microbiome is the totality of microorganisms present in the gastrointestinal tract. Gut microbial development in preterm infants is affected by environmental and genetic factors; however, the extent to which these factors play a role in shaping the preterm infant gut microbiome is poorly understood. Studying the gut microbiome of multiplets (twins and triplets) in relation to their environmental exposures, such as enteral feeding type, can provide insight into genetic versus environmental influences on the gut microbiome. We aimed …","PeriodicalId":275302,"journal":{"name":"Section on Neonatal-Perinatal Medicine Program","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130027325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-24DOI: 10.1542/PEDS.147.3_MEETINGABSTRACT.735
Melissa M. Carbajal, H. Karpen, Carly Gisondo, AnnaMarie Arias-Shah, M. Gray, H. French, M. Gillam-Krakauer, S. Izatt, E. Bonachea, Alison J Falck, L. Johnston, Allison H. Payne, Margarita M. Vasquez, P. Chess, R. Dadiz
{"title":"The Cost of Core Curriculum in Graduate Medical Education: A Cost Comparison of Didactic Educational Materials for Individual Fellowship Programs vs. Shared Flipped Classroom Materials from the National Neonatal Curriculum","authors":"Melissa M. Carbajal, H. Karpen, Carly Gisondo, AnnaMarie Arias-Shah, M. Gray, H. French, M. Gillam-Krakauer, S. Izatt, E. Bonachea, Alison J Falck, L. Johnston, Allison H. Payne, Margarita M. Vasquez, P. Chess, R. Dadiz","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.735","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.735","url":null,"abstract":"","PeriodicalId":275302,"journal":{"name":"Section on Neonatal-Perinatal Medicine Program","volume":"206 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132018986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-24DOI: 10.1542/PEDS.147.3_MEETINGABSTRACT.701
Sarah Kolnik, Kate Hildahl, Kylie A Corry, D. Moralejo, S. Juul, Elizabeth A. Nance, T. Wood
{"title":"Erythropoietin Mitigates Inflammatory and Oxidative Stress Responses to Oxygen-Glucose Deprivation (OGD) in a Ferret Organotypic Brain Slice Model","authors":"Sarah Kolnik, Kate Hildahl, Kylie A Corry, D. Moralejo, S. Juul, Elizabeth A. Nance, T. Wood","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.701","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.701","url":null,"abstract":"","PeriodicalId":275302,"journal":{"name":"Section on Neonatal-Perinatal Medicine Program","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128760817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-24DOI: 10.1542/PEDS.147.3_MEETINGABSTRACT.747
Morgan E Hardie, Amy L. Lesneski, S. Lakshminrusimha, Payam Vali
{"title":"Umbilical Cord Milking (UCM) During Positive Pressure Venitlation (PPV) Stablizes Hemoglobin but Increases Systemic Blood Pressure and Heart Rate In Perinatal Asphyxia","authors":"Morgan E Hardie, Amy L. Lesneski, S. Lakshminrusimha, Payam Vali","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.747","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.747","url":null,"abstract":"","PeriodicalId":275302,"journal":{"name":"Section on Neonatal-Perinatal Medicine Program","volume":"405 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113998398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-24DOI: 10.1542/PEDS.147.3_MEETINGABSTRACT.730
Paige K. Kube, Z. Aghai
Background: Routinetperformance of blood group and direct coombs test (DCT) on cord blood is controversial. At our institution, from 2007-2013, cord blood type and DCT was obtained for every newborn born to O positive mothers. For newborns with ABO incompatibility, first bilirubin check occurred at 6 hours of life. Phototherapy would commence in newborn nursery if needed with transfer to neonatal intensive care unit (NICU) for intensive phototherapy or additional intervention, including IVIG and exchange transfusion. Beginning 2014, routine cord blood group and DCT was no longer performed. First bilirubin level …
{"title":"Should We Screen Cord Blood For ABO Incompatibility?","authors":"Paige K. Kube, Z. Aghai","doi":"10.1542/PEDS.147.3_MEETINGABSTRACT.730","DOIUrl":"https://doi.org/10.1542/PEDS.147.3_MEETINGABSTRACT.730","url":null,"abstract":"Background: Routinetperformance of blood group and direct coombs test (DCT) on cord blood is controversial. At our institution, from 2007-2013, cord blood type and DCT was obtained for every newborn born to O positive mothers. For newborns with ABO incompatibility, first bilirubin check occurred at 6 hours of life. Phototherapy would commence in newborn nursery if needed with transfer to neonatal intensive care unit (NICU) for intensive phototherapy or additional intervention, including IVIG and exchange transfusion. Beginning 2014, routine cord blood group and DCT was no longer performed. First bilirubin level …","PeriodicalId":275302,"journal":{"name":"Section on Neonatal-Perinatal Medicine Program","volume":"164 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133654180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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