在/sup 18/FDG注射过程中,手指接受的剂量用蒙特卡罗模拟计算

C. Cordeiro, A. Maio, L. González, A. Gomes
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引用次数: 2

摘要

这项工作的主要目的是利用Geant3蒙特卡罗代码,评估PET医生手指中因使用/sup 18/FDG而产生的吸收剂量。并与热释光剂量计所得数据作了比较。使用PET放射性药物,如/sup 18/FDG,对手和手指有辐射危害。这项研究的一个动机是PET成像在核医学中的应用越来越多,而在相应的剂量测量和优化方面却没有相应的发展。考虑到每周10个病人的工作量,每个医生接受的手指剂量比每周皮肤剂量限制低3倍,如果手指在活动体积内,则低10倍。在计算中,假设典型的给药活动为0.185 GBq,手指注射器接触时间为10 s。对不同种类的注射器和不同的注射体积进行了蒙特卡罗计算。我们还计算了手指剂量作为三种壁材壁厚的函数。结果显示,当聚丙烯注射器被耐热塑料注射器取代时,剂量略有减少,并可用于制定含有最常用PET放射性药物的注射器的处理指南。
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Finger doses received during /sup 18/FDG injections calculated with Monte Carlo simulations
The main objective of this work is to evaluate the absorbed doses in the fingers of PET physicians derived from the administration of /sup 18/FDG, using the Geant3 Monte Carlo code. A comparison is made with data obtained with thermoluminiscent dosimeters. The administration of a PET radiopharmaceutical such as /sup 18/FDG presents a radiation hazard to the hands and fingers. One motivation for this study is the increased use of PET imaging in nuclear medicine that was not followed by a parallel development in the respective dose measurements and optimisation. Considering a workload of 10 patients per week, each medical doctor receives finger doses 3 times lower than the weekly skin dose limit with the fingers in the active volume and 10 times lower if they are in the rear end of the syringe. In the calculations it is assumed that a typical administered activity is 0.185 GBq with a finger-syringe contact time of 10 s. Monte Carlo calculations were performed for different kinds of syringes and different injected volumes. We have also calculated finger doses as a function of the wall thickness for three kinds of wall materials. Results show a slight dose reduction when the polypropylene syringe is replaced by a pyrex one and could be used to derive guidelines for the handling of syringes containing the most used PET radiopharmaceuticals.
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