纳米显微镜显示了肌共聚物h区和i带配合物的层状组织

Szilárd Szikora, T. Gajdos, Tibor Novák, Dávid Farkas, István Földi, P. Lénárt, M. Erdélyi, J. Mihály
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引用次数: 25

摘要

Szikora等人使用超分辨率显微镜在纳米级水平上揭示肌肉蛋白质的定位。通过这种蛋白质定位图谱和基于模板的蛋白质结构建模,他们组装了精细的i带和h区模型,并为肌肉形成提供了新的机制见解。
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Nanoscopy reveals the layered organization of the sarcomeric H-zone and I-band complexes
Szikora et al. use superresolution microscopy to reveal muscle protein localizations at the nanoscale level. With this protein localization atlas and template-based protein structure modeling, they assemble refined I-band and H-zone models and provide new mechanistic insights into sarcomerogenesis.
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