M. A. Bereketoğlu, Cemile Haki̇
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摘要

背景:我们的目的是确定影响冠状病毒病-2019 (COVID-19)大流行期间神经内科重症监护病房住院患者经皮内镜胃造口术(PEG)后死亡率和生存率的因素。回顾性分析了2020年2月至2021年5月在土耳其XXX医院神经内科重症监护病房住院期间接受PEG管插入的29例18岁及以上患者的临床和人口统计学资料。记录患者的人口统计学、临床特征和生存状况。结果:我们纳入了29例患者,其中女性16例,男性13例。幸存者的中位年龄为71岁(33-89岁),死亡的中位年龄为75.5岁(48-90岁)。两组在年龄(p = 0.119)和性别(p = 0.806)方面相似。术后死亡率为66%。置管后的平均总生存期为129.49天(95% CI: 91.21-167.78)。Cox回归显示,有多种合并症的患者死亡率增加了2.822倍(95% CI: 1.001-7.968, p = 0.049)。结论:这些发现表明,在COVID-19大流行期间入住神经内科重症监护病房的PEG接受者中,患有多种合并症是与死亡率相关的最重要因素。由于多种合并症导致较短的生存期,在这些患者中,似乎必须非常谨慎地决定插入PEG管。然而,需要进行更全面的研究来阐明COVID-19对PEG后死亡率和生存时间的影响。
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Nöroloji Yoğun Bakım Ünitesindeki Hastalarda Perkütan Endoskopik Gastrostomi Sonrası Sağkalım
Background: We aimed to determine factors affecting mortality and survival after Percutaneous endoscopic gastrostomy (PEG) in patients who were hospitalized in the neurology intensive care unit during the coronavirus disease-2019 (COVID-19) pandemic Materials and Methods: The clinical and demographic data of 29 patients aged 18 years and older who received PEG tube insertion during hospitalization in the Neurology Intensive Care Unit of XXX Hospital, Turkey, between February 2020 and May 2021 were examined retrospectively. Patients’ demographics, clinical characteristics, and survival status were recorded. Results: We included 29 patients (16 females and 13 males) into our study. Median age was 71 (33–89) years among survivors and 75.5 (48–90) years among those who died. The groups were similar with respect to age (p = 0.119) and sex (p = 0.806). Mortality rate after PEG insertion was 66%. Mean overall survival after PEG tube insertion was 129.49 days (95% CI: 91.21–167.78). Cox regression revealed that having multiple comorbidities increased the likelihood of mortality by 2.822-fold (95% CI: 1.001–7.968, p = 0.049). Conclusions: These findings show that having multiple comorbidities was the most important factor associated with mortality among PEG recipients who were admitted to the Neurology Intensive Care Unit during the COVID-19 pandemic. Since multiple comorbidities cause shorter survival, it appears that the decision to insert PEG tubes must be made extremely cautiously among these patients. However, more comprehensive studies should be conducted to clarify the effect of COVID-19 on mortality rates and survival time after PEG.
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