稀土掺杂纳米氧化物在生物标志物中的应用

International Conference on Oxide Materials for Electronic Engineering - fabrication, properties and applications (OMEE-2014) Pub Date : 2014-05-26 DOI:10.1109/OMEE.2014.6912345

M. Godlewski, J. Kaszewski, E. Wolska, M. Godlewski

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引用次数: 5

摘要

第一代生物标志物(荧光标记)是基于有机染料。为了取代它们，引入了高荧光CdTe、CdS和cdse生物标志物的纳米粒子(NPs)/量子点(QDs)。尽管这些NPs显示出一些有利的特性，但它们的使用受到闪烁、发射光谱扩散和镉使用的限制，在生物和医疗应用中应避免这些问题。这一事实促使我们使用生物相容性氧化物——ZnO、ZnAl2O4和ZrO2开发新一代生物标志物。它们的发射是由稀土离子掺杂激活的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Rare earth doped nanoparticles of oxides for biomarkers applications

First generation of biomarkers (fluorescence labels) is based on organic dyes. To replace them nanoparticles (NPs)/quantum dots (QDs) of highly fluorescent CdTe-, CdS- and CdSe-based biomarkers were introduced. Despite the fact that these NPs show some advantageous properties, their use is limited by blinking, spectral diffusion of emission and use of cadmium, which should be avoided in the case of biological and medical applications. This fact motivated us to develop new generation of biomarkers using biocompatible oxides - ZnO, ZnAl2O4 and ZrO2. Their emission is activated by doping with rare earth (RE) ions.

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International Conference on Oxide Materials for Electronic Engineering - fabrication, properties and applications (OMEE-2014)

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