Role of ACE gene polymorphism (RS4646994) in the pathogenesis of arterial hypertension formation in person performing task in the Arctic region

The results of content analysis of the role of polymorphism of the ACE gene genotype (RS4646994) in persons employed in the Arctic region are presented. It has been shown that it can be recommended as a universal marker in the diagnosis of not only essential hypertension, but other diseases of the cardiovascular system. In order to reduce the risk of developing pathological conditions, when planning official activities in the Arctic region, it is advisable to build professional selection, taking into account not only their genetic predisposition, but also the body's ability to maintain homeostasis. Key words: Arctic, polymorphism, ACE gene (RS4646994), arterial hypertension, homeostasis.