[外源性RNAse刺激作用的生化方面]。

A I Kolpakov, F G Kupriianova-Ashina
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引用次数: 0

摘要

研究了酵母菌从RNAse与细胞膜相互作用到细胞分裂的一系列生化反应。在生长培养基中添加RNAse可使细胞内Ca2+进入率提高2.4倍。在此条件下,细胞膜酶腺苷酸环化酶的增加与细胞内cAMP含量的增加有关,cAMP依赖性蛋白激酶活性升高。提出了一种假设的RNAse效应的细胞反应方案。
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[The biochemical aspects of the stimulating action of exogenous RNAse].

A sequence of biochemical reactions in yeast from moment of RNAse interaction with cell membrane to cell division has been studied. RNAse addition in growth medium causes the increase of Ca2+ entering rate in cells in 2.4 times. Under this condition the increase of membrane enzyme adenylate cyclase correlating with the growth of cAMP content in cell and rise of cAMP-dependent protein kinase activity have been observed. A hypothetic scheme of cellular response on the RNAse effect is suggested.

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