用于大规模时空分布神经组织刺激的多通道Asic设计

P. Hottowy, W. Dąbrowski, A. Skoczeń, P. Wia̧cek
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引用次数: 1

摘要

我们提出了一种设计用于神经组织电刺激的多电极阵列专用集成电路。ASIC预计将应用于需要同时刺激和记录来自各种神经组织的信号的系统,包括体外和体内。所开发的STIM64 ASIC包括64个独立的刺激通道,能够产生任意定义的双极电流或电压波形,实时控制,时间分辨率为50 μ m,幅度分辨率为7位。输出信号的幅度范围可以在一个非常宽的范围内缩放,这确保了与不同尺寸和几何形状的各种电极阵列的兼容性。每个通道都配备了实时控制的刺激伪影抑制器,减少了刺激脉冲和系统准备好记录信号之间的“死区时间”
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Design Of A Multichannel Asic For Large Scale Spatio-temporal Distributed Stimulation Of Neural Tissue
We present an ASIC designed for electrical stimulation of neural tissue using multielectrode arrays. The ASIC is foreseen for applications in systems requiring simultaneous stimulation and recording of signals from various types of neural tissue, both in-vitro and in-vivo. The developed STIM64 ASIC includes 64 independent stimulation channels, which are capable to generate arbitrarily defined bipolar current or voltage waveforms, controlled in real time with time resolution of 50 mus and amplitude resolution of 7 bits. The amplitude range of output signal can be scaled over a very wide range, what ensures compatibility with various electrode arrays of different size and geometry. Each channel is equipped with a real-time controlled stimulation artifact suppressor, which reduces the 'dead time' between the stimulation pulse and system being ready for signal recording
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