{"title":"基因选择的网络传播模型","authors":"Wei Zhang, Baryun Hwang, Baolin Wu, R. Kuang","doi":"10.1109/GENSIPS.2010.5719689","DOIUrl":null,"url":null,"abstract":"In this paper, we explore several network propagation methods for gene selection from microarray gene expression datasets. The network propagation methods capture gene co-expression and differential expression with unified machine learning frameworks. Large scale experiments on five breast cancer datasets validated that the network propagation methods are capable of selecting genes that are more biologically interpretable and more consistent across multiple datasets, compared with the existing approaches.","PeriodicalId":388703,"journal":{"name":"2010 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Network propagation models for gene selection\",\"authors\":\"Wei Zhang, Baryun Hwang, Baolin Wu, R. Kuang\",\"doi\":\"10.1109/GENSIPS.2010.5719689\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this paper, we explore several network propagation methods for gene selection from microarray gene expression datasets. The network propagation methods capture gene co-expression and differential expression with unified machine learning frameworks. Large scale experiments on five breast cancer datasets validated that the network propagation methods are capable of selecting genes that are more biologically interpretable and more consistent across multiple datasets, compared with the existing approaches.\",\"PeriodicalId\":388703,\"journal\":{\"name\":\"2010 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS)\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2010 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/GENSIPS.2010.5719689\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2010 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/GENSIPS.2010.5719689","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
In this paper, we explore several network propagation methods for gene selection from microarray gene expression datasets. The network propagation methods capture gene co-expression and differential expression with unified machine learning frameworks. Large scale experiments on five breast cancer datasets validated that the network propagation methods are capable of selecting genes that are more biologically interpretable and more consistent across multiple datasets, compared with the existing approaches.