黄曲霉毒素:对家禽的毒性作用及其治疗的最新进展

Yasir Allah Ditta, S. Mahad, U. Bacha
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引用次数: 11

摘要

在世界上,特别是在非洲、亚洲和拉丁美洲,大约25%的农产品被黄曲霉毒素和其他真菌毒素污染,完全损失了约2%至3%的粮食价值,从而给农民造成经济损失。食品供应链中的霉菌毒素污染主要影响人类和动物健康,而生产是第二大问题,特别是在发展中国家。黄曲霉毒素(无色至淡黄色晶体)是研究最多的一类真菌毒素(>5000篇研究文章)。在亚热带地区,AFs在健康、生长、饲料转化率等方面造成了重大问题。在农产品中,在植物生长、收获和储存过程中预防真菌污染似乎是避免真菌毒素的最有效和合理的预防措施。活性炭;铝硅酸盐;聚合物,如聚乙烯吡咯烷酮和胆苯胺;酵母、酵母制品和腐植酸也得到了广泛的研究,结果有希望,但不尽相同。一种名为酿酒酵母(酿酒酵母)的活酵母也被观察到可以减轻家禽黄曲霉中毒的不良影响。这些有益的作用后来归因于葡甘露聚糖,是从酿酒酵母的细胞壁中提取的。
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Aflatoxins: Their Toxic Effect on Poultry and Recent Advances in Their Treatment
About 25% of total agriculture products are contaminated with aflatoxins (AFs) and other mycotoxins in the world especially in Africa, Asia and Latin America, completely losing about 2 – 3% of food values and thus causing economic losses to farmers. The mycotoxin contaminations of food supply chain impact on human and animal health primarily, whereas production is the second major concern especially in developing countries. Aflatoxins (colorless to pale yellow colored crystals) are the most studied (>5000 research articles) group of mycotoxins. AFs impose major problems regarding health, growth, FCR (feed conversion ratio), etc. in the subtropical zone. In the agricultural commodities, the prevention of fungal contamination during plant growth, harvesting and storage seems to be the most effective and rational precautionary measures to avoid mycotoxins. Activated charcoal; aluminosilicates; polymers, such as polyvinyl pyrrolidones and chole-styramine; and yeast, yeast-based products, and humic acid have been studied extensively with promising but variable results. A live yeast, named Saccharomyces cerevisiae ( S. cerevisiae ), has also been observed to lighten the adverse effects of aflatoxicosis in poultry. These beneficial effects were later attributed to glucomannan, being derived from the cell wall of S. cerevisiae .
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Co-Occurrence of Mycotoxins and Its Detoxification Strategies Control of Aflatoxicosis in Poultry Using Probiotics and Polymers Aflatoxins: Their Toxic Effect on Poultry and Recent Advances in Their Treatment Aflatoxin Management Strategies in Sub-Saharan Africa The Socio-Economic Impact of Mycotoxin Contamination in Africa
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