Zabol新生儿先天性畸形患病率:一项基于单一医院的研究

Mojtaba Jahantiq, M. Mazaheri, Tayebeh Rabaninia, A. Javaheri, Nooshin Amjadi
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引用次数: 1

摘要

背景:先天性异常是指出生时就存在的、可能影响婴儿健康、发育和生存的先天性异常。先天性畸形新生儿的出生给家庭带来了经济和情感上的负担。本研究的目的是调查2014年伊朗Zabol先天性异常的流行病学。方法:本横断面研究于2013年5月至2014年4月在Amir Al-Momenin医院进行。所有活产儿都包括在内,我们检查了所有新生儿是否存在先天性异常。结果:在12个月内,9309名新生儿被纳入研究。其中72例(0.8%)新生儿患有先天性畸形。男性新生儿先天性畸形发生率(66.7%)明显高于女性新生儿(33.3%)。其中,肌肉骨骼系统异常占所有异常的45.9%,其自身的异常频率最高。其次是中枢神经系统异常(19.4%)、胃肠道异常(15.3%)、泌尿道异常(9.7%)、染色体异常(2.8%)和多发性异常(1.4%)。结论:本研究显示扎布勒市先天性畸形患病率居高不下。本研究的结果确定了遗传咨询和早期诊断对预防、护理和监测的必要性。
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Prevalence of Congenital Anomalies in Newborns in Zabol: A Single Hospital Based Study
Background: Congenital anomalies are conditions of prenatal origin that are present at birth, potentially impacting an infant's health, development and survival. The birth of a newborn with congenital anomalies imposes financial and emotional burdens on families. The aim of this study was to investigate the epidemiology of congenital anomalies in 2014 in Zabol, Iran.   Methods: This cross-sectional study was carried out in the Amir Al-Momenin Hospital between May of 2013 and April 2014. All the live born were included, and we have examined all newborns for the presence of congenital anomalies.   Results: During the twelve months, 9,309 newborns were included to the study. Of them, 72 (0.8%) newborns were affected with a congenital malformation. The congenital anomalies affected significantly higher proportion of male newborns (66.7%) than female newborns (33.3%). Among of them, musculoskeletal system abnormalities account for 45.9% of the total abnormalities allocating the highest frequency to itself. Subsequently, central nervous system abnormality (19.4%), gastrointestinal anomaly (15.3%), urinary tract abnormality (9.7%), chromosomal abnormality (2.8%), and multiple anomalies (1.4%) were frequent, respectively.   Conclusion: This study showed that prevalence of congenital anomalies is restively high in Zabol city. The results of this study identify the necessity of genetic counseling and early diagnosis to prevention, care and surveillance.
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