J. Mooney, K. Morris, S. Jacobs, E. Lefebvre, G. Cosgrove, S. Wong, J. Bellini, M. Jurek, S. Turner, M. Decaris, R. Jiron, B. Williams, H. Duan, R. Gunn, G. Rizzo, M. Wardak, H.H. Guo
{"title":"整合素αvβ6和αvβ1的双选择性抑制剂PLN-74809在特发性肺纤维化(IPF)患者的肺中显示剂量依赖性靶标作用","authors":"J. Mooney, K. Morris, S. Jacobs, E. Lefebvre, G. Cosgrove, S. Wong, J. Bellini, M. Jurek, S. Turner, M. Decaris, R. Jiron, B. Williams, H. Duan, R. Gunn, G. Rizzo, M. Wardak, H.H. Guo","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5254","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":179165,"journal":{"name":"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS","volume":"37 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"PLN-74809, a Dual-Selective Inhibitor of Integrins αvβ6 and αvβ1, Shows Dose-Dependent Target Engagement in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF)\",\"authors\":\"J. Mooney, K. Morris, S. Jacobs, E. Lefebvre, G. Cosgrove, S. Wong, J. Bellini, M. Jurek, S. Turner, M. Decaris, R. Jiron, B. Williams, H. Duan, R. Gunn, G. Rizzo, M. Wardak, H.H. Guo\",\"doi\":\"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5254\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":179165,\"journal\":{\"name\":\"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS\",\"volume\":\"37 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5254\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"D30. THE INJURED LUNG: MECHANISMS AND THERAPEUTIC TARGETS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5254","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
PLN-74809, a Dual-Selective Inhibitor of Integrins αvβ6 and αvβ1, Shows Dose-Dependent Target Engagement in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF)