Antibiotic susceptibility of staphylococcus aureus strains isolated from various clinical specimens in a tertiary hospital

Aims: Staphylococcus aureus infection rates, which are the cause of infections, have rapidly risen in both hospitals and society, constituting a concern. In this study, it was aimed to examine the antibiotic susceptibility of S. aureus strains isolated from patients treated in a tertiary state hospital for four years. Methods: A retrospective analysis was performed on S. aureus strains (n=584) identified from clinical samples delivered to the medical microbiology laboratory of Niğde Ömer Halisdemir University Training and Research Hospital for bacterial culture between 2016 and 2019. The isolates were identified by standard laboratory procedure. VITEK 2 automated system (bioMerieux, France) was used to identification and antibiotic susceptibilities of evaluate the strains. Results: Strains were most commonly isolated from wound swab (n=173) and blood culture (n=107). While the highest resistance rate was observed against Erythromycin (n=232), the least amikacin (n=16) resistant strain was determined. Vancomycin and teicoplanin resistance was not observed. Conclusion: Multi-drug resistance and MRSA resistance still exist today. The absence of vancomycin and teicoplanin resistance, in addition to the low level of trimethoprim-sulfamethoxazole resistance, is encouraging. This information about S. aureus's susceptibility may be helpful in determining how to administer antibiotics.