Value of Increasing the Reliability of Diagnosis of Nonclassical Congenital Adrenal Hyperplasia with Use of LC- MS/ MS in escalating the Diagnostic Capacity of Women with Clinical hyperandrogenism-A Short Communication

Congenital adrenal hyperplasia (CAH) represents a disorder that takes place secondary to the deficiency of the adrenal enzymes, most commonly 21 hydroxylases (21OH) along with the commonest autosomal recessive condition in humans. In case of milder non canonical type (NCCAH), normal quantities are generated at the cost of adrenocorticotropic hormone quantities that in turn results in Clinical hyperandrogenism that gets presented from childhood via early adult period. A remarkable resemblance of signs along with symptoms with those of Polycystic ovary syndrome (PCOS). Hence NCCAH constitutes a significant differential diagnosis, in case of women manifesting acne, hirsutism, menstrual aberrations along with infertility