伊鲁替尼诱导感觉运动神经病变:一种新的副作用

Dipanjan Panda, Disha Tiwari, Atul Sharma, D. Kishan
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引用次数: 0

摘要

化疗引起的周围神经病变(CIPN)是一种有充分证据的毒性导致剂量限制。伊鲁替尼是一种口服布鲁顿酪氨酸激酶(BTK)抑制剂,被批准用于治疗慢性淋巴细胞淋巴瘤。伊鲁替尼最常见的神经系统副作用包括头痛和头晕。在这里,我们报告周围神经病变是伊鲁替尼治疗的剂量限制表现。
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Ibrutinib induced sensorimotor neuropathy: A novel side effect
Chemotherapy-induced peripheral neuropathy (CIPN) is a well-documented toxicity leading to dose limitation.Ibrutinib is an oral Bruton’s Tyrosine Kinase (BTK) inhibitor approved for treating chronic lymphocytic lymphoma. The most common neurological side effects of Ibrutinib include headache and dizziness. Herein, we report peripheral neuropathy as a dose-limiting manifestation of Ibrutinib treatment.
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