基于网格的睡眠研究:使用网格基础设施的多导睡眠图分析

D. Krefting, S. Canisius, A. Hoheisel, H. Loose, T. Tolxdorff, T. Penzel
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引用次数: 10

摘要

生物信号的分析,如脑电图(EEG)或心电图(ECG),在许多医学领域的诊断是必不可少的,特别是睡眠医学和睡眠研究。该领域的标准方法是多导睡眠描记术,这是一种在整个就寝阶段记录多维生物信号的方法。在SIESTA项目中,一个欧洲多中心研究,收集了300多人的综合临床和多导睡眠记录。为了使研究人员可以使用数据作为临床研究和开发新分析工具的参考,SIESTA数据库被实现到网格基础设施中。迄今为止,完整的数据存储在网格中,并实现了不同的自动心电分析算法。可以对数据库进行查询,并在记录级和收集级对匹配数据进行分析。应用程序被建模为工作流,并使用工作流管理器集成到网格中。图形用户界面作为网格portlet实现。它允许初始化新的计算任务,以及监视和从已经启动的分析中检索结果。
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Grid-Based Sleep Research: Analysis of Polysomnographies Using a Grid Infrastructure
The analysis of biosignals, such as the electroencephalogram EEG or the electrocardiogram (ECG), is essential for diagnosis in many medical areas, in particular sleep medicine and sleep research. A standard method in this field is the polysomnography, a multidimensional biosignal recording during the whole bedtime phase. Within the SIESTA project, a European multicenter study, comprehensive clinical and polysommnographic records from over 300 persons has been collected. To make the data available for researchers as reference for clinical research and development of new analysis tools, the SIESTA database is implemented into a grid infrastructure. To date, the complete data is stored into the grid and different algorithms for automated ECG analysis are implemented. The database can be queried and the matching data can be analysed on record level and collection level. The application is modelled as a workflow and integrated into the grid using a workflow manager. A graphical user interface is implemented as a grid portlet. It allows the initialization of new computation tasks as well as the monitoring and result-retrieval from already launched analyses.
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