用于脑机接口的微图案化无创干电极

F. Gramatica, R. Carabalona, M. Casella, C. Cepek, E. Di Fabrizio, M. Di Rienzo, L. Gavioli, M. Matteucci, F. Rizzo, M. Sancrotti
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引用次数: 8

摘要

部分或完全瘫痪的患者可以从先进的神经假肢中受益,这种假肢需要连续记录脑电图(EEG),进行一些处理和分类,以控制计算机(BCI,脑机接口)。病人可以控制外部设备或通过电脑交流简单的信息,只需将注意力集中在编码的动作或数字键盘上的字母或图标上。传统的电极通常需要皮肤制备和应用电解凝胶来进行高质量的低振幅生物电位记录,并且不适合患者或护理人员在BCI或等效系统中轻松使用。在本报告中,我们描述了干燥(不需要凝胶),非侵入性,用户友好的生物电位电极的制造和表征。电极由微针的二维阵列组成,设计用于刺穿第一介电皮肤层(角质层),并与表皮中的活细胞和导电细胞(没有血管和神经末梢)建立直接接触。尖刺电极的简单和直接的应用使它们对每一个表面的长期生物信号测量也很有吸引力,甚至在病人家里(脑电图,心电图等)。
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Micropatterned non-invasive dry electrodes for Brain-Computer Interface
Partially or completely paralyzed patients can benefit from advanced neuro-prostheses in which a continuous recording of electroencephalogram (EEG) is required, operating some processing and classification to control a computer (BCI, brain-computer interfaces). Patients are so allowed to control external devices or to communicate simple messages through the computer, just concentrating their attention on codified movements or on a letter or icon on a digital keyboard. Conventional electrodes usually require skin preparation and application of electrolytic gel for high quality low amplitude biopotentials recordings and are not suitable for being easily used by patient or caregivers at home in BCI or equivalent systems. In this report we describe the fabrication and characterization of dry (gel not required), non-invasive, user-friendly biopotential electrodes. The electrodes consist of a bidimensional array of micro-needles designed to pierce the first dielectric skin layer (stratum corneum) and establishing a direct contact with the living and electrical conducting cells in the epidermis (no blood vessels and nerve terminations). The easy and immediate application of the spiked electrodes makes them also attractive for every surface long-term biosignal measurements, even at patient's home (EEG, electrocardiogram, etc).
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