浆果补充剂及其对中枢神经系统疾病的有益作用

Fernández-Demeneghi Rafael, Vargas-Moreno Isidro, Acosta-Mesa Héctor-Gabriel, P. Abraham, Campos-Uscanga Yolanda, Romo-González Tania, Guzmán-Gerónimo Rosa-Isela, Patraca-Camacho Lorena, Herrera-Meza Socorro
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引用次数: 1

摘要

本章是基于不同的体外、临床前和临床研究的汇编和分析,这些研究探讨了补充浆果对中枢神经系统(CNS)某些改变的潜在有益生物活性。本章的最后一部分描述了浆果中存在的多酚、花青素和其他化合物的可能作用机制,以及它们与焦虑、抑郁、阿尔茨海默病(AD)和帕金森病(PD)的关系,以及它们在预防认知能力下降和运动功能衰老方面的意义。使用Springer、PubMed、Scopus和Elsevier等电子数据库。论文是按主题选择的,特别是那些与浆果、出版年份和作者有关的论文。本章证明了不同浆果及其生物活性化合物(主要是类黄酮、多酚和花青素)作为神经保护剂对焦虑、抑郁、阿尔茨海默病和帕金森病等疾病的潜在健康影响。总之,对于人类营养来说,莓果补充剂可能是一种极好的抗氧化剂来源,也是预防和减轻诸如焦虑、抑郁、阿尔茨海默氏症和帕金森症等疾病症状的替代选择。
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Berry Supplementation and Their Beneficial Effects on Some Central Nervous System Disorders
This chapter is based in the compilation and analysis of different in vitro, preclinical, and clinical studies, which explored the potential beneficial bioactiv-ity of supplementation with berries on some alterations in the central nervous system (CNS). The last section of the chapter describes the possible mechanisms of action of polyphenols, anthocyanins, and other compounds present in berries as well as their relationship with anxiety, depression, and Alzheimer’s (AD) and Parkinson’s diseases (PD) and their implication in the prevention of cognitive decline and senescence motor functions. Electronic databases as Springer, PubMed, Scopus, and Elsevier were used. Papers were selected by topic specially those related with berries, year of publication, and authors. The present chapter evidenced the potential health effect as neuroprotector of different berries and their bioactive compounds mainly flavonoids, polyphenols, and anthocyanins, on diseases such as anxiety, depression, and Alzheimer’s and Parkinson’s diseases. In conclusion, for human nutrition berry fruit supplementation might be an excellent source of antioxidant and alternative for prevention and reduction of symptoms in diseases such as anxiety, depression, Alzheimer’s, and Parkinson’s.
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