甲状腺风暴作为一种危及生命的疾病在医疗急救队伍中的实践

Agnieszka Ciastkowska-Berlikowska
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摘要

甲状腺风暴是一种医疗紧急情况。它包括几个器官和身体系统的紊乱,包括意识障碍(也包括昏迷)、心力衰竭、休克症状和高体温。甲状腺风暴的诊断是具有挑战性的,因为它主要基于病史和体格检查。额外的实验室检查仅起辅助作用,治疗的开始不应延迟至血液中甲状腺激素的测定。此外,临床症状往往与血液中甲状腺激素浓度无关。腹泻、呕吐和发烧可导致甲状腺风暴的诊断。这些都不是单纯甲亢的典型症状。甲状腺风暴的其余症状是个别器官和系统失代偿的症状。当诊断甲状腺风暴时,人们使用Burch和Wartofsky标准。准确、快速的诊断和实施初期治疗是院前管理的目标。这些是液体疗法、氧气疗法和退烧药。出于这个原因,不延误病人到最近的医院急诊科是至关重要的。你也可以考虑叫一辆有医生的专科救护车,医生可以在现场给你正确的药物。快速开始治疗可在12-24小时内改善大多数患者的状况。治疗延误加重,强化治疗可改善甲状腺风暴患者的预后。甲状腺风暴的死亡率已经下降,目前为20-30%。
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THYROID STORM AS A LIFE-THREATENING CONDITION IN THE PRACTICE OF EMERGENCY MEDICAL SERVICE TEAMS
Thyroid storm is a medical emergency. It comprises disorders of several organs and body systems, including disturbances of consciousness (also coma), heart failure, symptoms of shock, and high body temperature. The diagnosis of thyroid storm is challenging because it is based primarily on medical history and physical examination. Additional laboratory tests only perform an auxiliary function, and the initiation of therapy should not be delayed until the determination of thyroid hormones in the blood. Moreover, clinical symptoms often do not correlate with thyroid hormones concentration in the blood. Diarrhea, vomiting, and fever may lead to the diagnosis of thyroid storm. These are not typical symptoms of uncomplicated hyperthyroidism. The remaining symptoms of thyroid storm are symptoms of decompensation of individual organs and systems. When diagnosing thyroid storm, one uses the Burch and Wartofsky criteria. Accurate and quick diagnosis and implementation of initial treatment is the aim of pre-hospital management. These are fluid therapy, oxygen therapy, and antipyretic drugs. For this reason, it is essential not to delay the patient’s transport to the nearest hospital emergency department. One may also consider calling a specialist ambulance with a doctor who can give the right medication on the spot. Rapid treatment initiation can improve the status of most patients within 12-24 hours. Treatment delay worsens, and intensive treatment improves the prognosis in patients with thyroid storm. The mortality rate of thyroid storm has decreased and is now 20-30%.
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