Wolfgang Weber , Hans Zähner , Manfred Damberg , Peter Russ , Axel Zeeck
{"title":"病原体201说明:\"旁通A和B","authors":"Wolfgang Weber , Hans Zähner , Manfred Damberg , Peter Russ , Axel Zeeck","doi":"10.1016/S0721-9571(81)80035-X","DOIUrl":null,"url":null,"abstract":"<div><p><em>Streptomyces collinus ssp. collinus (Lindenbein)</em> strain Tü 1892 produces ansatrienin A and B which show antifungal activity. Bacteria are not or only weakly inhibited. From a chemical point of view ansatrienins are members of the ansamycin antibiotics. They have a 1,4-benzoquinone resp. hydroquinone nucleus, and moreover an ansa bridge consisting of 18 links which shows an isolated triene part. The colourless ansatrienin B is oxidized into the yellow ansatrienin A with the molecular formula C<sub>36</sub>H<sub>48</sub>N<sub>2</sub>O<sub>8</sub>. The ansatrienins contain a N-cyclohexylcarbonyl-alanine side chain which is linked to the ansa bridge like an ester.</p><p>The structure elements of the ansatrienins are related to the maytansinoids.</p></div>","PeriodicalId":101290,"journal":{"name":"Zentralblatt für Bakteriologie Mikrobiologie und Hygiene: I. Abt. Originale C: Allgemeine, angewandte und ?kologische Mikrobiologie","volume":"2 2","pages":"Pages 122-139"},"PeriodicalIF":0.0000,"publicationDate":"1981-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0721-9571(81)80035-X","citationCount":"4","resultStr":"{\"title\":\"Stoffwechselprodukte von mikroorganismen 201. Mitteilung: Ansatrienin A und B, fungistatische antibiotika aus Streptomyces collinus\",\"authors\":\"Wolfgang Weber , Hans Zähner , Manfred Damberg , Peter Russ , Axel Zeeck\",\"doi\":\"10.1016/S0721-9571(81)80035-X\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><em>Streptomyces collinus ssp. collinus (Lindenbein)</em> strain Tü 1892 produces ansatrienin A and B which show antifungal activity. Bacteria are not or only weakly inhibited. From a chemical point of view ansatrienins are members of the ansamycin antibiotics. They have a 1,4-benzoquinone resp. hydroquinone nucleus, and moreover an ansa bridge consisting of 18 links which shows an isolated triene part. The colourless ansatrienin B is oxidized into the yellow ansatrienin A with the molecular formula C<sub>36</sub>H<sub>48</sub>N<sub>2</sub>O<sub>8</sub>. The ansatrienins contain a N-cyclohexylcarbonyl-alanine side chain which is linked to the ansa bridge like an ester.</p><p>The structure elements of the ansatrienins are related to the maytansinoids.</p></div>\",\"PeriodicalId\":101290,\"journal\":{\"name\":\"Zentralblatt für Bakteriologie Mikrobiologie und Hygiene: I. Abt. Originale C: Allgemeine, angewandte und ?kologische Mikrobiologie\",\"volume\":\"2 2\",\"pages\":\"Pages 122-139\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1981-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0721-9571(81)80035-X\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zentralblatt für Bakteriologie Mikrobiologie und Hygiene: I. Abt. Originale C: Allgemeine, angewandte und ?kologische Mikrobiologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S072195718180035X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zentralblatt für Bakteriologie Mikrobiologie und Hygiene: I. Abt. Originale C: Allgemeine, angewandte und ?kologische Mikrobiologie","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S072195718180035X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Stoffwechselprodukte von mikroorganismen 201. Mitteilung: Ansatrienin A und B, fungistatische antibiotika aus Streptomyces collinus
Streptomyces collinus ssp. collinus (Lindenbein) strain Tü 1892 produces ansatrienin A and B which show antifungal activity. Bacteria are not or only weakly inhibited. From a chemical point of view ansatrienins are members of the ansamycin antibiotics. They have a 1,4-benzoquinone resp. hydroquinone nucleus, and moreover an ansa bridge consisting of 18 links which shows an isolated triene part. The colourless ansatrienin B is oxidized into the yellow ansatrienin A with the molecular formula C36H48N2O8. The ansatrienins contain a N-cyclohexylcarbonyl-alanine side chain which is linked to the ansa bridge like an ester.
The structure elements of the ansatrienins are related to the maytansinoids.
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