分类结果部分报告的影响

Mohammadmahdi R. Yousefi, Jianping Hua, Chao Sima, E. Dougherty
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引用次数: 0

摘要

当提出一种新的分类方案时,可能是以分类规则或特征选择方法的形式,生物信息学文献中的建模者通常会报告其在感兴趣的数据集(如基因表达微阵列)上的性能。这些数据集通常包含数千个特征,但样本点数量很少,这增加了特征选择和误差估计的可变性,导致报告的性能非常不精确。这表明,如果只展示最佳结果,所提出方案的报告性能与实际性能的相关性较小,并且与实际性能存在高度偏差。本文通过展示最小报告估计误差和相应的真实误差的联合分布的行为作为在使用模型和实际数据的大型模拟研究中测试的样本数量的函数来证实这一点。
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Effects of partial reporting of classification results
When proposing a new classification scheme, perhaps in the form of a classification rule or feature selection method, modelers in the bioinformatics literature typically report its performance on data sets of interest, such as gene-expression microarrays. These data sets often include thousands of features but a small number of sample points, which increases variability in feature selection and error estimation, resulting in highly imprecise reported performances. This suggests that the reported performance of the proposed scheme would be less correlated with and highly biased from the actual performance if only the best results are demonstrated. This paper confirms this by showing the behavior of the joint distributions of the minimum reported estimated errors and corresponding true errors as functions of the number of samples tested in a large simulation study using both modeled and real data.
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