糖尿病耳聋不同证型患者甲状旁腺激素和骨钙素的变化

Li Ruiyu, Li Yue, L. Xing, L. Meng, Guo Weiya, Zhang Chenyu, L. Qingwen, Hou Jinjie
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摘要

目的:观察不同证型糖尿病患者甲状旁腺激素和骨钙素的变化。方法:检测39例(50耳)不同类型糖尿病合并耳聋患者甲状旁腺激素(I-PTH)和骨钙素(BGP)的变化。对照组为20名正常人。结果:糖尿病伴耳聋患者血清I-PTH水平与正常对照组比较无显著变化(P>0.05),而糖尿病伴耳聋患者血清I-PTH水平有显著变化(P>0.05)。气阴虚组和阴阳虚组血钙素水平与正常组比较差异均有统计学意义(P<0.05, P<0.01)。与阴虚、干燥组比较(P<0.05);与阴虚干热组(P<0.01)、气虚阴虚组(P<0.01)比较,阴虚干热组与气虚干热组(P<0.01)比较,阴虚干热组与气虚干热组(P<0.01)比较。结论:不同证型糖尿病患者甲状旁腺激素和骨钙素的变化将为糖尿病的预防和治疗提供客观依据。
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Changes of Parathyroid Hormone and Osteocalcin in Diabetic Patients with Different Syndromes of Deafness
Objective: To observe the changes of parathyroid hormone and osteocalcin in diabetic patients with different syndromes. Methods: The changes of parathyroid hormone (I-PTH) and osteocalcin (BGP) in 39 patients (50 ears) with different types of diabetes mellitus and deafness were detected. The control group was 20 normal people. Results: The level of I-PTH in diabetic patients with deafness had no significant change compared with the normal control group (P >0.05), but the level of I-PTH in diabetic patients with deafness had significant change (P>0.05). The level of BGP in qi-yin deficiency group and yin-yang deficiency group was significantly changed compared with the normal group (P<0.05, P<0.01). Compared with Yin deficiency and desiccation (P<0.05); Compared with Yin deficiency and desiccation heat (P<0.01) and qi deficiency and Yin deficiency (P<0.01), the two groups of Yin deficiency and desiccation heat (P<0.01) were compared. Conclusion: The changes of parathyroid hormone and osteocalcin in diabetic patients with different syndromes will provide objective evidence for the prevention and treatment of diabetes.
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