基于在体内和离体测量中进行的介电特性分析的年龄和大小的乳腺肿瘤分类

E. Fernandez-Aranzamendi, E. San-roman, P. Castillo‐Araníbar, Luz-Ventura, V. González-Posadas, D. Segovia-Vargas
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引用次数: 3

摘要

区分乳腺健康组织和癌组织的介电特性对乳腺癌的早期检测研究至关重要。基于体内和离体电介质测量肿瘤乳房的报道不多。此外,女性在乳房组织(皮肤、脂肪、腺体和肿瘤)之间的介电参数表现出高度的可变性。本研究的重点是在体内和离体乳房和肿瘤组织的测量和分析,在1至8 GHz的频率范围内,基于介质协议测量,使用开放式同轴探头。结果对肿瘤进行了早期、中期、晚期的分类、大小和类型。这些测量是在乳房切除术和乳房肿瘤切除术中进行的,每组测量都考虑相同的压力,通过一个调节的压力系统,温度从22度到27度不等,所有这些测量和参数都由病理学家验证。因此,在控制系统方案下,在区分中老年乳腺肿瘤与健康乳腺方面观察到一些差异,即乳腺良性和恶性异常所在区域的实际介电常数和电导率增加。
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Breast tumor classification by age and size based on analysis of dielectric properties performed on in vivo and ex vivo measurements
Differentiating the dielectric properties of the breast between healthy and cancerous tissues is essential to contribute to the early detection studies of breast cancer. There are not many reports based on in vivo and ex vivo dielectric measurements on breasts with tumor. In addition, women show high variability of dielectric parameters between breast tissues (skin, fat, gland, and tumors). This study focuses on the measurement and analysis of breast and tumor tissues in vivo and ex vivo, over a frequency range of 1 to 8 GHz, based on dielectric protocol measurement, using an open coaxial probe. The result led to make a tumor classification (early, middle, and advanced), size and type. These measurements were made in mastectomy and lumpectomy surgeries, considering the same pressure for each group of measurements through a regulated pressure system, with a temperature varies from 22 to 27 degrees, all these measurement and parameters validated by a pathologist. As a result, some differences are observed in distinguishing breasts with tumors from healthy breasts in middle and advanced ages, under a controlled system protocol, that is, increases in real permittivity and conductivity in the breast over the areas where benign and malignant anomalies were located.
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