E. Gieva, R. Rusev, G. Angelov, R. Radonov, M. Hristov
{"title":"类似于β -内酰胺酶蛋白Michaelis复合体中氢键网络的微电子电路","authors":"E. Gieva, R. Rusev, G. Angelov, R. Radonov, M. Hristov","doi":"10.1109/ISSE.2014.6887608","DOIUrl":null,"url":null,"abstract":"A microelectronic circuit of block-elements functionally analogous to two hydrogen bonding networks is investigated in the present paper. The hydrogen bonding networks are extracted from Michaelis complex of β-lactamase protein. They are described by electrical circuits. The hydrogen bonds of the networks are presented by three- or four-terminal block-elements in the juxtaposed electrical circuits. The block-elements are coded in Matlab with polynomials and static and dynamic analyses are performed. The circuits' behavior appeared to be similar to current source or amplifier, and signal modulator.","PeriodicalId":375711,"journal":{"name":"Proceedings of the 2014 37th International Spring Seminar on Electronics Technology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2014-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Microelectronic circuits analogous to hydrogen bonding networks in Michaelis complex of beta-lactamase protein\",\"authors\":\"E. Gieva, R. Rusev, G. Angelov, R. Radonov, M. Hristov\",\"doi\":\"10.1109/ISSE.2014.6887608\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A microelectronic circuit of block-elements functionally analogous to two hydrogen bonding networks is investigated in the present paper. The hydrogen bonding networks are extracted from Michaelis complex of β-lactamase protein. They are described by electrical circuits. The hydrogen bonds of the networks are presented by three- or four-terminal block-elements in the juxtaposed electrical circuits. The block-elements are coded in Matlab with polynomials and static and dynamic analyses are performed. The circuits' behavior appeared to be similar to current source or amplifier, and signal modulator.\",\"PeriodicalId\":375711,\"journal\":{\"name\":\"Proceedings of the 2014 37th International Spring Seminar on Electronics Technology\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2014-05-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the 2014 37th International Spring Seminar on Electronics Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ISSE.2014.6887608\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 2014 37th International Spring Seminar on Electronics Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ISSE.2014.6887608","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Microelectronic circuits analogous to hydrogen bonding networks in Michaelis complex of beta-lactamase protein
A microelectronic circuit of block-elements functionally analogous to two hydrogen bonding networks is investigated in the present paper. The hydrogen bonding networks are extracted from Michaelis complex of β-lactamase protein. They are described by electrical circuits. The hydrogen bonds of the networks are presented by three- or four-terminal block-elements in the juxtaposed electrical circuits. The block-elements are coded in Matlab with polynomials and static and dynamic analyses are performed. The circuits' behavior appeared to be similar to current source or amplifier, and signal modulator.