{"title":"抗抑郁药的抗溃疡作用。2抗抑郁药inkazan、azafen和of -743联合精氨酸对乙醇诱发的大鼠胃黏膜损伤的影响[j]。","authors":"N A Natsvlishvili, G E Samonina, I P Ashmarin","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Mucosal gastric damages in rats induced by intragastric ethanol introduction decreased considerably on the background of action of one of the antidepressants (asaphen, inkasan and OF-743) in combination with arginine. The combination OF-743 with arginine has the largest protective action, the least one--asaphen with arginine. A comparison of protective action of some antidepressants with action of antidepressants in combination with arginine revealed a tendency to more expressed antiulcerogenic effect in studied combinations.</p>","PeriodicalId":18920,"journal":{"name":"Nauchnye doklady vysshei shkoly. Biologicheskie nauki","volume":" 7","pages":"52-7"},"PeriodicalIF":0.0000,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The antiulcer action of antidepressants. II. The effect of the antidepressants inkazan, azafen, and OF-743 in combination with arginine on ethanol-evoked damage to the gastric mucosa in rats].\",\"authors\":\"N A Natsvlishvili, G E Samonina, I P Ashmarin\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Mucosal gastric damages in rats induced by intragastric ethanol introduction decreased considerably on the background of action of one of the antidepressants (asaphen, inkasan and OF-743) in combination with arginine. The combination OF-743 with arginine has the largest protective action, the least one--asaphen with arginine. A comparison of protective action of some antidepressants with action of antidepressants in combination with arginine revealed a tendency to more expressed antiulcerogenic effect in studied combinations.</p>\",\"PeriodicalId\":18920,\"journal\":{\"name\":\"Nauchnye doklady vysshei shkoly. Biologicheskie nauki\",\"volume\":\" 7\",\"pages\":\"52-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nauchnye doklady vysshei shkoly. Biologicheskie nauki\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nauchnye doklady vysshei shkoly. Biologicheskie nauki","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[The antiulcer action of antidepressants. II. The effect of the antidepressants inkazan, azafen, and OF-743 in combination with arginine on ethanol-evoked damage to the gastric mucosa in rats].
Mucosal gastric damages in rats induced by intragastric ethanol introduction decreased considerably on the background of action of one of the antidepressants (asaphen, inkasan and OF-743) in combination with arginine. The combination OF-743 with arginine has the largest protective action, the least one--asaphen with arginine. A comparison of protective action of some antidepressants with action of antidepressants in combination with arginine revealed a tendency to more expressed antiulcerogenic effect in studied combinations.