毛细管周细胞:展望与未来趋势。

R G Tilton
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引用次数: 108

摘要

全面了解微循环需要充分了解每个组成细胞(包括周细胞)的结构和功能。近二十年来,人们对血管内皮和平滑肌细胞进行了深入的研究,但对毛细血管周细胞的代谢和功能却知之甚少。然而,新的电子显微镜技术的发展,新的细胞培养和分子生物学技术的应用,应该允许快速阐明细胞生物化学和微血管功能和病理这种无处不在的毛细血管细胞。
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Capillary pericytes: perspectives and future trends.

A complete understanding of the microcirculation requires full knowledge of the structure and function of each of the constituent cells, including pericytes. Vascular endothelium and smooth muscle cells have been investigated intensively during the last two decades, but much less is known about the metabolism and function of capillary pericytes. However, the development of new electron microscopy techniques and the application of new cell culture and molecular biology techniques should allow for the rapid elucidation of the cellular biochemistry and the microvascular function and pathology of this ubiquitous capillary cell.

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Real time computer simulation of transmission electron microscope images with tilted illumination: grain boundary applications. Cryofixation of vascular endothelium. The endothelial vesicle system in cryofixed frog mesenteric capillaries analysed by ultrathin serial sectioning. Lectin and immunolabeling of microvascular endothelia. Quick-freeze, deep-etch studies of endothelial components, with special reference to cytoskeletons and vesicle structures.
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