微流控芯片实验室在生物医学中的应用

A. T. Giannitsis, M. Min
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引用次数: 17

摘要

片上实验室系统包括一类在单个芯片上集成流体和电子的设备。芯片实验室设备能够处理和分析化学和生物液体样品。微流控装置包括一个更广泛的组,包括芯片上的实验室设备和微总分析系统(μTAS)。前者专门用于实验室使用,例如样品测试和处理,而后者主要侧重于分子水平的生化分析。芯片实验室设备促进自动化操作,如样品处理,分离和液体混合。此外,芯片实验室设备推动了即时护理设备的发展,这有望成为个性化医疗诊断和治疗的领先技术。
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Usage of microfluidic lab-on-chips in biomedicine
Lab-on-chip systems comprise a class of devices that integrate fluidics and electronics on a single chip. Lab-on-chip devices are capable of handling and analysing chemical and biological liquid samples. Microfluidic devices comprise a broader group that includes lab-on-chip devices and also micro total analysis systems (μTAS). The formers are devoted to laboratory use, such as sample testing and handling, while the latter focuses mostly on biochemical analysis down to molecular level. Lab-on-chip devices facilitate automated operations such as sample handling, separation and liquid mixing. Furthermore, lab-on-chip devices force the development of point-of-care devices, which are expected to become the leading technology for diagnosis and therapeutics in personalized medicine.
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