{"title":"通过机器学习和纳米技术设计疫苗以终止COVID-19大流行","authors":"Hyunjo Kim, Jae-Hoon Song, South Korea Ansorp","doi":"10.47363/JVRR/2020(1)122","DOIUrl":null,"url":null,"abstract":"The COVID-19 vaccine development involves high-tech platforms such as viral vectors, antigen carriers, and delivery technology. Nanotechnology tools can play a pivotal role in advancing COVID-19 treatment and vaccine design. Information related to the structural morphology of the SARS-CoV-2 virus, its pathophysiology, and related immunological response is the most important factor at the nanotechnology point of view. In the absence of a specific antiviral against SARS- CoV-2, present therapeutics target the multifaceted molecular interactions involved in viral infections and major comprises repurposing already existing antiviral molecules used for other RNA viruses. Furthermore, various kinds of vaccine candidate’s structure could be screened by using ma- chine learning. Recently, it is equally important to look for a suitable Nano-carrier delivery technology to make these repurposed therapeutics as well as new vaccine development safer and more effective affordable methodologies so that nanotechnology can reach patients.","PeriodicalId":247504,"journal":{"name":"Journal of Virology Research & Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Vaccine Design through Machine Learning and Nanotechnology to Terminate COVID-19 Pandemic\",\"authors\":\"Hyunjo Kim, Jae-Hoon Song, South Korea Ansorp\",\"doi\":\"10.47363/JVRR/2020(1)122\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The COVID-19 vaccine development involves high-tech platforms such as viral vectors, antigen carriers, and delivery technology. Nanotechnology tools can play a pivotal role in advancing COVID-19 treatment and vaccine design. Information related to the structural morphology of the SARS-CoV-2 virus, its pathophysiology, and related immunological response is the most important factor at the nanotechnology point of view. In the absence of a specific antiviral against SARS- CoV-2, present therapeutics target the multifaceted molecular interactions involved in viral infections and major comprises repurposing already existing antiviral molecules used for other RNA viruses. Furthermore, various kinds of vaccine candidate’s structure could be screened by using ma- chine learning. Recently, it is equally important to look for a suitable Nano-carrier delivery technology to make these repurposed therapeutics as well as new vaccine development safer and more effective affordable methodologies so that nanotechnology can reach patients.\",\"PeriodicalId\":247504,\"journal\":{\"name\":\"Journal of Virology Research & Reports\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-12-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Virology Research & Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47363/JVRR/2020(1)122\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Virology Research & Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47363/JVRR/2020(1)122","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Vaccine Design through Machine Learning and Nanotechnology to Terminate COVID-19 Pandemic
The COVID-19 vaccine development involves high-tech platforms such as viral vectors, antigen carriers, and delivery technology. Nanotechnology tools can play a pivotal role in advancing COVID-19 treatment and vaccine design. Information related to the structural morphology of the SARS-CoV-2 virus, its pathophysiology, and related immunological response is the most important factor at the nanotechnology point of view. In the absence of a specific antiviral against SARS- CoV-2, present therapeutics target the multifaceted molecular interactions involved in viral infections and major comprises repurposing already existing antiviral molecules used for other RNA viruses. Furthermore, various kinds of vaccine candidate’s structure could be screened by using ma- chine learning. Recently, it is equally important to look for a suitable Nano-carrier delivery technology to make these repurposed therapeutics as well as new vaccine development safer and more effective affordable methodologies so that nanotechnology can reach patients.