Objective: To describe the prevalence and incidence of suspected COVID-19 cases confirmed by PCR at Medical Center ISSEMyM Toluca from March 2019 to December 2022. Materials and Methods: 3226 PCR tests for suspected COVID-19 cases were analyzed to obtain epidemiological and demographic data of the population, descriptive and inferential statistics analyses were carried out to find differences between population parameters. Results: No differences between female and male respect to COVID-19 positivity were found (p-value = 0.9302). Age mean was 49 years old and the probability to get COVID-19 increase with age (p-value = 0.000). Hospitalization was the medical service with more frequency in patients with COVID-19 positive. Conclusion: Age but no gender is a risk factor hospitalization due COVID-19., nonetheless vaccination appear to an efficient method to prevent hospitalization. Moreover, the dynamic pandemic in Mexico is no homogeneous across the territory.
{"title":"Epidemiological and Demographic Analysis of Suspected Covid-19 Cases Confirmed by PCR at Medical Center ISSEMyM Toluca from March 2019 to December 2022","authors":"Sánchez-Flores Jesús Enrique, Santillán-Benítez Jonnathan Guadalupe","doi":"10.47363/jvrr/2023(4)160","DOIUrl":"https://doi.org/10.47363/jvrr/2023(4)160","url":null,"abstract":"Objective: To describe the prevalence and incidence of suspected COVID-19 cases confirmed by PCR at Medical Center ISSEMyM Toluca from March 2019 to December 2022. Materials and Methods: 3226 PCR tests for suspected COVID-19 cases were analyzed to obtain epidemiological and demographic data of the population, descriptive and inferential statistics analyses were carried out to find differences between population parameters. Results: No differences between female and male respect to COVID-19 positivity were found (p-value = 0.9302). Age mean was 49 years old and the probability to get COVID-19 increase with age (p-value = 0.000). Hospitalization was the medical service with more frequency in patients with COVID-19 positive. Conclusion: Age but no gender is a risk factor hospitalization due COVID-19., nonetheless vaccination appear to an efficient method to prevent hospitalization. Moreover, the dynamic pandemic in Mexico is no homogeneous across the territory.","PeriodicalId":247504,"journal":{"name":"Journal of Virology Research & Reports","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135032810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The anti-tumour cytokine TNFα is involved in signalling apoptosis of infected cells. The aim of this study was to evaluate the immune response mediated by TNFα during HPV infection in women with precancerous and cancerous lesions of the uterine cervix in a Congolese population. Method: A total of 181 women underwent cervico-vaginal sampling for cervico-vaginal smears and HPV testing. A blood sample on EDTA tube was also taken to measure plasma TNFα concentrations. Papanicolaoum staining was used for the cervicovaginal smear. HPV testing was performed by real-time PCR on the CFX 96 automated system using the Anyplex II HPV28 kit (Seegene).Third-generation enzyme-linked immunosorbent assay (ELISA) was used to etermine plasma TNFα concentrations using the “Elisa TNFα Pars Biochem” Kit (Nanjing Pars Biochem Co., LTD China) according to the manufacturer’s instructions. Results: The mean age of the women was 39.8 ± 12.7 years, with a raté of 22.7% of anormal cytologies. The prévalence of HPV was 66.2%. TNFα Levels in patients with précancéreuse and cancers lésions ère signifiant hier thane in women with normal cytologie (p<0.0001). Mean TNFα concentrations ère 76.1ng/l for HPV-positive and 35.9 nm/l for HPV-négative (p<0.0001). TNFα concentrations ère élevâtes in sujets with high-ris HPV génotypes (82.6ng/l) compare with loris génotypes (72.6ng/l). Conclusion: Our résulte shoge élevâtes plasma TNFα Levels in patients with précancéreuse and cancers cervical lésions. This élévation was alto corrélâtes with oncogénique HPV génotypes.
抗肿瘤细胞因子TNFα参与感染细胞凋亡的信号传导。本研究的目的是评估刚果人群中宫颈癌前病变和癌性病变妇女HPV感染期间TNFα介导的免疫反应。方法:共有181名妇女接受宫颈阴道涂片和HPV检测。同时取血EDTA管，测定血浆TNFα浓度。宫颈阴道涂片采用帕氏染色法。使用Anyplex II HPV28试剂盒(Seegene)在CFX 96自动化系统上进行实时PCR检测。采用第三代酶联免疫吸附法(ELISA)测定血浆tnf - α浓度，使用“ELISA tnf - α Pars Biochem”试剂盒(中国南京Pars生物化学有限公司)，按照制造商的使用说明。结果:女性平均年龄39.8±12.7岁，细胞学异常比例为22.7%。HPV感染率为66.2%。患有前列腺癌和前列腺癌的患者的TNFα水平明显高于细胞学正常的女性(p < 0.01;0.0001)。hpv阳性患者的平均TNFα浓度为76.1ng/l, hpv阴性患者的平均TNFα浓度为35.9 nm/l (p<0.0001)。高危型人乳头瘤病毒携带者体内TNFα浓度(82.6ng/l)高于高危型人乳头瘤病毒携带者(72.6ng/l)。结论:我们的研究表明:与宫颈肿瘤患者的血浆TNFα水平有关。这一变异体与肿瘤型的HPV变异体完全一致。
{"title":"Evaluation of the Immune Response by TNFα During Cervico-Uterine HPV Infection in Congo","authors":"Paola Candyse Tsimba Lemba, Luc Magloire Anicet Boumba","doi":"10.47363/jvrr/2023(4)159","DOIUrl":"https://doi.org/10.47363/jvrr/2023(4)159","url":null,"abstract":"Introduction: The anti-tumour cytokine TNFα is involved in signalling apoptosis of infected cells. The aim of this study was to evaluate the immune response mediated by TNFα during HPV infection in women with precancerous and cancerous lesions of the uterine cervix in a Congolese population. Method: A total of 181 women underwent cervico-vaginal sampling for cervico-vaginal smears and HPV testing. A blood sample on EDTA tube was also taken to measure plasma TNFα concentrations. Papanicolaoum staining was used for the cervicovaginal smear. HPV testing was performed by real-time PCR on the CFX 96 automated system using the Anyplex II HPV28 kit (Seegene).Third-generation enzyme-linked immunosorbent assay (ELISA) was used to etermine plasma TNFα concentrations using the “Elisa TNFα Pars Biochem” Kit (Nanjing Pars Biochem Co., LTD China) according to the manufacturer’s instructions. Results: The mean age of the women was 39.8 ± 12.7 years, with a raté of 22.7% of anormal cytologies. The prévalence of HPV was 66.2%. TNFα Levels in patients with précancéreuse and cancers lésions ère signifiant hier thane in women with normal cytologie (p<0.0001). Mean TNFα concentrations ère 76.1ng/l for HPV-positive and 35.9 nm/l for HPV-négative (p<0.0001). TNFα concentrations ère élevâtes in sujets with high-ris HPV génotypes (82.6ng/l) compare with loris génotypes (72.6ng/l). Conclusion: Our résulte shoge élevâtes plasma TNFα Levels in patients with précancéreuse and cancers cervical lésions. This élévation was alto corrélâtes with oncogénique HPV génotypes.","PeriodicalId":247504,"journal":{"name":"Journal of Virology Research & Reports","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-30DOI: 10.47363/jvrr/2023(4)147
Poonam Sethi
Tobacco Necrotic Virus (TNV) is a plant disease affecting most of the legumes and other vegetable crops. The primary symptom being abnormal coloring or necrotic tissue in the leaves. Currently only chemical control of the virus is possible. There are, however, cultural management options to reduce the risk of the virus. The ‘ABC’ of TNV is (A) refers to dark brown raised patches, (B) dark sunken lesions (C) light brown cracked patches. Gunapaselam is a plant tonic made with fish extracts along with jaggery .Serial dilutions of the Fish Tonic ranging from1, 10,100 to 1000µl were applied to the host plant Cyamopsis tetragonoloba (Cluster Bean).The promising levels being 100 µl.Gunapaselam was applied as a liquid foliar spray.
{"title":"Anti Phytoviral Activities of Gunapaselam, On Tobacco Necrotic Virus (Tnv) Affecting Cyamopsis Tetragonoloba L (Taub)","authors":"Poonam Sethi","doi":"10.47363/jvrr/2023(4)147","DOIUrl":"https://doi.org/10.47363/jvrr/2023(4)147","url":null,"abstract":"Tobacco Necrotic Virus (TNV) is a plant disease affecting most of the legumes and other vegetable crops. The primary symptom being abnormal coloring or necrotic tissue in the leaves. Currently only chemical control of the virus is possible. There are, however, cultural management options to reduce the risk of the virus. The ‘ABC’ of TNV is (A) refers to dark brown raised patches, (B) dark sunken lesions (C) light brown cracked patches. Gunapaselam is a plant tonic made with fish extracts along with jaggery .Serial dilutions of the Fish Tonic ranging from1, 10,100 to 1000µl were applied to the host plant Cyamopsis tetragonoloba (Cluster Bean).The promising levels being 100 µl.Gunapaselam was applied as a liquid foliar spray.","PeriodicalId":247504,"journal":{"name":"Journal of Virology Research & Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136002430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-31DOI: 10.47363/jvrr/2021(2)136
Richmond Ronald Gomes
Dengue is a mosquito-borne disease (female mosquitoes of the Aedes genus, principally Aedes aegypti) caused by any one of four closely related dengue viruses. It is endemic in tropical and subtropical continent. World health organization (WHO) currently estimates there may be 50 -100 million dengue infections worldwide every year with over 2.5 billion people at risk of dengue. Symptomatic dengue virus infection may manifests as undifferentiated fever, classical dengue fever (with or without unusual hemorrhages), and dengue hemorrhagic fever (with or without shock). Isolated organopathy or expanded dengue syndrome (EDS) was coined by WHO in the year 2012 to describe cases, which do not fall into either dengue shock syndrome or dengue hemorrhagic fever. The atypical manifestations noted in expanded dengue are multisystemic and multifaceted with organ involvement, such as liver, brain, heart, kidney, central/peripheral nervous system, gastrointestinal tract, lympho reticular system. Dengue virus has long been considered as a non-neurotropic virus, as animal studies have shown that virus does not cross blood brain barrier. Hyponatremia may be found in association with dengue fever and is thought to be caused by peripheral fluid extravasation and resulting intravascular hypovolaemia. But hyponatremia due to syndrome of inappropriate secretion of anti-diuretic hormone (SIADH) in Dengue fever is rare. We report a 40 years old male who was diagnosed as Dengue fever (Dengue Ns1Ag positive) with thrombocytopenia and hyponatremia. He was admitted and further investigations revealed SIADH. He responded well to cautious sodium replacement and addition of tolvaptan. He recovered completely and was discharged after one week. Thus, all clinicians should keep in mind the possibility of SIADH as a part of expanded dengue syndrome.
{"title":"SIADH (Syndrome of Inappropriate ADH Secretion): Perplexing Look of Dengue Fever","authors":"Richmond Ronald Gomes","doi":"10.47363/jvrr/2021(2)136","DOIUrl":"https://doi.org/10.47363/jvrr/2021(2)136","url":null,"abstract":"Dengue is a mosquito-borne disease (female mosquitoes of the Aedes genus, principally Aedes aegypti) caused by any one of four closely related dengue viruses. It is endemic in tropical and subtropical continent. World health organization (WHO) currently estimates there may be 50 -100 million dengue infections worldwide every year with over 2.5 billion people at risk of dengue. Symptomatic dengue virus infection may manifests as undifferentiated fever, classical dengue fever (with or without unusual hemorrhages), and dengue hemorrhagic fever (with or without shock). Isolated organopathy or expanded dengue syndrome (EDS) was coined by WHO in the year 2012 to describe cases, which do not fall into either dengue shock syndrome or dengue hemorrhagic fever. The atypical manifestations noted in expanded dengue are multisystemic and multifaceted with organ involvement, such as liver, brain, heart, kidney, central/peripheral nervous system, gastrointestinal tract, lympho reticular system. Dengue virus has long been considered as a non-neurotropic virus, as animal studies have shown that virus does not cross blood brain barrier. Hyponatremia may be found in association with dengue fever and is thought to be caused by peripheral fluid extravasation and resulting intravascular hypovolaemia. But hyponatremia due to syndrome of inappropriate secretion of anti-diuretic hormone (SIADH) in Dengue fever is rare. We report a 40 years old male who was diagnosed as Dengue fever (Dengue Ns1Ag positive) with thrombocytopenia and hyponatremia. He was admitted and further investigations revealed SIADH. He responded well to cautious sodium replacement and addition of tolvaptan. He recovered completely and was discharged after one week. Thus, all clinicians should keep in mind the possibility of SIADH as a part of expanded dengue syndrome.","PeriodicalId":247504,"journal":{"name":"Journal of Virology Research & Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122551298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-31DOI: 10.47363/jvrr/2021(2)135
Sameer Yousof Rizg, Saleh H Alkhalid, E. Saleh
Objectives - To assess the prevalence of major depression among medical students. - To assess the risk factors of major depression among medical students. Background: Depression, a common mental disorder which has been considered a serious problem worldwide. Depression has a great negative impact on different aspects of a person’s life such as school performance, work productivity, relationships with family and friends, and ability to participate and become an active member in the community Design: cross sectional study. Review Methods and Data Sources: A survey has been conduct seeking respondents’ level of agreement rating scale with a series of statements of two questionnaire sections: Depression Anxiety Stress Scale (DASS21), and Medical Student Stressor Questionnaire (MSSQ). Data gathered through an online questionnaire that designed through method mentioned above and distributed to preclinical and clinical medical students at King Saud bin Abdulaziz University for Health Sciences, Jeddah. The study will be conducted at King Saud Bin Abdulaziz University for Health Sciences- Jeddah, Saudi Arabia. Results: The prevalence of depression anxiety stress for study participants 11.6%. The prevalence of medical student stressor scale rich about 6.1%. There is significant different depression anxiety stress scale according to gender of participants. Top 10 Statements out of 21 of depression anxiety stress scale according to respondents’ opinions are: 1. I felt that I was using a lot of nervous energy. 2. I found it difficult to work up the initiative to do things. 3. I found it hard to wind down. 4. I found it difficult to relax. 5. I found myself getting agitated. 6. I was worried about situations in which I might panic and make a fool of myself. 7. I felt downhearted and blue. 8. I experienced trembling (eg, in the hands). 9. I was unable to become enthusiastic about anything. 10. I was aware of dryness of my mouth. Conclusion: This study was prompted by the rise in depression anxiety disorder is considered the leading cause of disability worldwide. The results and discussion sections presented high prevalence of depression anxiety stress rich 11.6% within the study sample of the preclinical and clinical medical students at King Saud bin Abdulaziz University for Health Sciences, Jeddah. Since the prevalence of medical student stressor rich 6.1% for same sample size.
{"title":"The prevalence and factors associated with depression among preclinical and clinical medical students at King Saud bin Abdulaziz University for Health Sciences, Jeddah","authors":"Sameer Yousof Rizg, Saleh H Alkhalid, E. Saleh","doi":"10.47363/jvrr/2021(2)135","DOIUrl":"https://doi.org/10.47363/jvrr/2021(2)135","url":null,"abstract":"Objectives - To assess the prevalence of major depression among medical students. - To assess the risk factors of major depression among medical students. Background: Depression, a common mental disorder which has been considered a serious problem worldwide. Depression has a great negative impact on different aspects of a person’s life such as school performance, work productivity, relationships with family and friends, and ability to participate and become an active member in the community Design: cross sectional study. Review Methods and Data Sources: A survey has been conduct seeking respondents’ level of agreement rating scale with a series of statements of two questionnaire sections: Depression Anxiety Stress Scale (DASS21), and Medical Student Stressor Questionnaire (MSSQ). Data gathered through an online questionnaire that designed through method mentioned above and distributed to preclinical and clinical medical students at King Saud bin Abdulaziz University for Health Sciences, Jeddah. The study will be conducted at King Saud Bin Abdulaziz University for Health Sciences- Jeddah, Saudi Arabia. Results: The prevalence of depression anxiety stress for study participants 11.6%. The prevalence of medical student stressor scale rich about 6.1%. There is significant different depression anxiety stress scale according to gender of participants. Top 10 Statements out of 21 of depression anxiety stress scale according to respondents’ opinions are: 1. I felt that I was using a lot of nervous energy. 2. I found it difficult to work up the initiative to do things. 3. I found it hard to wind down. 4. I found it difficult to relax. 5. I found myself getting agitated. 6. I was worried about situations in which I might panic and make a fool of myself. 7. I felt downhearted and blue. 8. I experienced trembling (eg, in the hands). 9. I was unable to become enthusiastic about anything. 10. I was aware of dryness of my mouth. Conclusion: This study was prompted by the rise in depression anxiety disorder is considered the leading cause of disability worldwide. The results and discussion sections presented high prevalence of depression anxiety stress rich 11.6% within the study sample of the preclinical and clinical medical students at King Saud bin Abdulaziz University for Health Sciences, Jeddah. Since the prevalence of medical student stressor rich 6.1% for same sample size.","PeriodicalId":247504,"journal":{"name":"Journal of Virology Research & Reports","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133098291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-31DOI: 10.47363/jvrr/2021(2)125
Hossam B. Bahnasy
Diabetes mellitus (DM) is a metabolic chronic disease that represents a high global incidence rate. Glycated hemoglobin (HbA1C) is the long - term glucose reference test it appears to be associated with chronic diabetes complications, (Hb A1C) is not recommended for use in clinical situations that may interfere with metabolism of hemoglobin, as in hemolytic anemia, secondary or iron deficiency, hemoglobinopathies, pregnancy, and uremia.Glycated albumin (GA) is ashort term blood sugar test that is not affected by cases that incorrectly change A1c leveles.GA is the top part of glucose of fructosamine. It is meashured by the standard enzyme methodology, easy and fast performance.These Laboratory properties have ensured the spotlight on GA in studies from the past decade,as asign of monitoring and screening for diabetes as well as predicting long –term outcomes of the disease . The aim of this review was to discuss the physiological and biochemistry characteristics of the GA, as well as its clinical utility in DM.
{"title":"Clinical Biochemistry Impact of Glycated Albumin as a Potential Biomarker in Diabetes","authors":"Hossam B. Bahnasy","doi":"10.47363/jvrr/2021(2)125","DOIUrl":"https://doi.org/10.47363/jvrr/2021(2)125","url":null,"abstract":"Diabetes mellitus (DM) is a metabolic chronic disease that represents a high global incidence rate. Glycated hemoglobin (HbA1C) is the long - term glucose reference test it appears to be associated with chronic diabetes complications, (Hb A1C) is not recommended for use in clinical situations that may interfere with metabolism of hemoglobin, as in hemolytic anemia, secondary or iron deficiency, hemoglobinopathies, pregnancy, and uremia.Glycated albumin (GA) is ashort term blood sugar test that is not affected by cases that incorrectly change A1c leveles.GA is the top part of glucose of fructosamine. It is meashured by the standard enzyme methodology, easy and fast performance.These Laboratory properties have ensured the spotlight on GA in studies from the past decade,as asign of monitoring and screening for diabetes as well as predicting long –term outcomes of the disease . The aim of this review was to discuss the physiological and biochemistry characteristics of the GA, as well as its clinical utility in DM.","PeriodicalId":247504,"journal":{"name":"Journal of Virology Research & Reports","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127339337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-31DOI: 10.47363/jvrr/2021(2)124
Porntep Siriwanarangsun, A. Cheepsattayakorn, th Zonal Tuberculosis
Volume 2(1): 1-1 A recent study in China demonstrated that the rapid surge of COVID-19 in healthcare workers (HCWs) may be the lack of effective protection measures. This study revealed that there were no significant differences in the use of gloves or medical masks among the three group of 1) intensive care unit (ICU) staff, 2) staff working in the fever outpatient department, general patient room, Fangcang shelter hospital, emergency department, cleaning area, imaging examination area, and transfer vehicle, and 3) staff working in the general outpatient department, community, pharmacy, and administrative area. Nevertheless, all other types of personal protective equipment (PPE) (N95/FFP2 respirator, face shield/goggles, isolation gown, medical protective uniform, and positive pressure headgear) were used most group 1 and HCWs in group 2. Skin injury was the most common type (62.3 %) of PPE-associated adverse events (87.3 %), dyspnea (61.8 %), dizziness (57.8 %), and headache (53.8 %). Greater risks of adverse events occurred in both doctors (30.2 %) and nurses (66.5 %) compared to other types of HCWs (3.3 %, both p < 0.05). The negative results of the reverse-transcriptase-polymerasechain-reaction tests in all three group participants accompanying negative results of serological tests in 70 % of all participants suggested the efficacious measure of PPE for the SARS-CoV-2 (COVID-19) nosocomial transmission. The need for guidance on rationalizing, prioritizing, and grading the PPE use due to HCWs’ infection risk is supported by the efficacy of different PPE among HCWs in different working areas. The basic emergency guidance of PPE for protecting HCWs should be issued at the earliest stage of an epidemic, not months later. Although 98.6 % of HCWs revealed high adherence level to PPE protocols, PPE was commonly related to adverse events in the study participants both physically and psychologically.
{"title":"Personal Protective Equipment Interventions in the Era of COVID-19 Pandemics","authors":"Porntep Siriwanarangsun, A. Cheepsattayakorn, th Zonal Tuberculosis","doi":"10.47363/jvrr/2021(2)124","DOIUrl":"https://doi.org/10.47363/jvrr/2021(2)124","url":null,"abstract":"Volume 2(1): 1-1 A recent study in China demonstrated that the rapid surge of COVID-19 in healthcare workers (HCWs) may be the lack of effective protection measures. This study revealed that there were no significant differences in the use of gloves or medical masks among the three group of 1) intensive care unit (ICU) staff, 2) staff working in the fever outpatient department, general patient room, Fangcang shelter hospital, emergency department, cleaning area, imaging examination area, and transfer vehicle, and 3) staff working in the general outpatient department, community, pharmacy, and administrative area. Nevertheless, all other types of personal protective equipment (PPE) (N95/FFP2 respirator, face shield/goggles, isolation gown, medical protective uniform, and positive pressure headgear) were used most group 1 and HCWs in group 2. Skin injury was the most common type (62.3 %) of PPE-associated adverse events (87.3 %), dyspnea (61.8 %), dizziness (57.8 %), and headache (53.8 %). Greater risks of adverse events occurred in both doctors (30.2 %) and nurses (66.5 %) compared to other types of HCWs (3.3 %, both p < 0.05). The negative results of the reverse-transcriptase-polymerasechain-reaction tests in all three group participants accompanying negative results of serological tests in 70 % of all participants suggested the efficacious measure of PPE for the SARS-CoV-2 (COVID-19) nosocomial transmission. The need for guidance on rationalizing, prioritizing, and grading the PPE use due to HCWs’ infection risk is supported by the efficacy of different PPE among HCWs in different working areas. The basic emergency guidance of PPE for protecting HCWs should be issued at the earliest stage of an epidemic, not months later. Although 98.6 % of HCWs revealed high adherence level to PPE protocols, PPE was commonly related to adverse events in the study participants both physically and psychologically.","PeriodicalId":247504,"journal":{"name":"Journal of Virology Research & Reports","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128378882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-20DOI: 10.47363/jvrr/2021(2)126
L. Deac
Diarrhea had to be understood from medical point of view, as an alteration in a normal bowel movement characterized by an increase in the water content, volume, or frequency of stools. Acute diarrhea of infec¬tious etiology, referred to gastroenteri¬tis and is associated with clinical signs and symptoms including: nausea, vomiting, abdomi¬nal pain and cramps, bloating, flatulence, fever, passage of bloody stools, tenesmus, and fecal ur-gency disorders. In fact, Infectious diarrheal diseases, are the second leading cause of morbidity and mortality worldwide and can cause real public health problems. Such diarrhea was studied as a medical disorder, in a 3 year period, 2017-2020, in Transylvania region from Romania. We have found out 3577 number of cases, data which were transmitted by 12 district Sanitary Polices, to the Public Health Center. This all were mostly diagnosed by the territorial family doctors and more than 50%, have need hospitalization, for several days, because of several disease disorders. The detected infectious etiology, were determined in authorized laboratories, by identified: Shigella spp, Salmonella spp, Campylobacter spp, Yersinia spp, Rotavirus, Giardia. Most number of cases appeared in children, followed by elderly or adult people, as quantified number of determined infectious diarrheas. Acute diarrheal illness had to be considered a major public health issue, against which control efforts are needed. Public health surveillance of infectious acute diarrhea, include obligatory strategies of infection control.
{"title":"Infectious Diarrhea, As Public Health Problem, In Romania","authors":"L. Deac","doi":"10.47363/jvrr/2021(2)126","DOIUrl":"https://doi.org/10.47363/jvrr/2021(2)126","url":null,"abstract":"Diarrhea had to be understood from medical point of view, as an alteration in a normal bowel movement characterized by an increase in the water content, volume, or frequency of stools. Acute diarrhea of infec¬tious etiology, referred to gastroenteri¬tis and is associated with clinical signs and symptoms including: nausea, vomiting, abdomi¬nal pain and cramps, bloating, flatulence, fever, passage of bloody stools, tenesmus, and fecal ur-gency disorders. In fact, Infectious diarrheal diseases, are the second leading cause of morbidity and mortality worldwide and can cause real public health problems. Such diarrhea was studied as a medical disorder, in a 3 year period, 2017-2020, in Transylvania region from Romania. We have found out 3577 number of cases, data which were transmitted by 12 district Sanitary Polices, to the Public Health Center. This all were mostly diagnosed by the territorial family doctors and more than 50%, have need hospitalization, for several days, because of several disease disorders. The detected infectious etiology, were determined in authorized laboratories, by identified: Shigella spp, Salmonella spp, Campylobacter spp, Yersinia spp, Rotavirus, Giardia. Most number of cases appeared in children, followed by elderly or adult people, as quantified number of determined infectious diarrheas. Acute diarrheal illness had to be considered a major public health issue, against which control efforts are needed. Public health surveillance of infectious acute diarrhea, include obligatory strategies of infection control.","PeriodicalId":247504,"journal":{"name":"Journal of Virology Research & Reports","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128254747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-30DOI: 10.47363/JVRR/2020(1)115
Seyi S. Enitan, S. Junaid, R. Akele
The quest for a safe and effective HIV vaccine holds life-saving potential for people globally. Interestingly, the HIV/COVID-19 overlapping pandemic have impacted each other in diverse ways, some being advantageous, while others detrimental. On one hand, the HIV platforms for development of rapid test kits, neutralizing antibodies, vaccine development and trials, collaboration and mobilization etc. has proved very helpful and a promising template for the development of interventions for the COVID-19 pandemic; while on the other hand, a number of ongoing HIV vaccine safety and efficacy trials are being abridged, stopped or suspended amidst the Coronavirus Disease-19 (COVID-19) crisis. The COVID-19 outbreak that begun in Wuhan, megacity of China late December, 2019, has spread to 220 countries and territories, with more than 36 million total confirmed cases and 1,057,505 total deaths globally as at 08 October, 2020 and still counting. Currently, no approved vaccines exist to prevent infection with the novel Coronavirus, however, the impact of the pandemic has been enormous with devastating effects on the global health and economy, with many countries introducing stringent response measures to de-escalate the spread of the virus. Recruiting and retaining volunteers for HIV vaccine trials this period has become very challenging due to a lot of factors including fear of potential exposure to the new coronavirus, ethical issues and safety concerns amongst others. The protection and safety of participants and clinic staff remain a priority for HIV vaccine investigators worldwide. They are at the moment making conscious efforts to execute measures necessary to prevent potential exposure and transmission of COVID-19 among study participants and clinic staff in various study sites. This review takes a look at the overlapping impacts of the HIV/COVID-19 pandemic on HIV vaccine development.
{"title":"Overlapping Impacts of HIV/COVID-19 Pandemic on HIV Vaccine Development","authors":"Seyi S. Enitan, S. Junaid, R. Akele","doi":"10.47363/JVRR/2020(1)115","DOIUrl":"https://doi.org/10.47363/JVRR/2020(1)115","url":null,"abstract":"The quest for a safe and effective HIV vaccine holds life-saving potential for people globally. Interestingly, the HIV/COVID-19 overlapping pandemic have impacted each other in diverse ways, some being advantageous, while others detrimental. On one hand, the HIV platforms for development of rapid test kits, neutralizing antibodies, vaccine development and trials, collaboration and mobilization etc. has proved very helpful and a promising template for the development of interventions for the COVID-19 pandemic; while on the other hand, a number of ongoing HIV vaccine safety and efficacy trials are being abridged, stopped or suspended amidst the Coronavirus Disease-19 (COVID-19) crisis. The COVID-19 outbreak that begun in Wuhan, megacity of China late December, 2019, has spread to 220 countries and territories, with more than 36 million total confirmed cases and 1,057,505 total deaths globally as at 08 October, 2020 and still counting. Currently, no approved vaccines exist to prevent infection with the novel Coronavirus, however, the impact of the pandemic has been enormous with devastating effects on the global health and economy, with many countries introducing stringent response measures to de-escalate the spread of the virus. Recruiting and retaining volunteers for HIV vaccine trials this period has become very challenging due to a lot of factors including fear of potential exposure to the new coronavirus, ethical issues and safety concerns amongst others. The protection and safety of participants and clinic staff remain a priority for HIV vaccine investigators worldwide. They are at the moment making conscious efforts to execute measures necessary to prevent potential exposure and transmission of COVID-19 among study participants and clinic staff in various study sites. This review takes a look at the overlapping impacts of the HIV/COVID-19 pandemic on HIV vaccine development.","PeriodicalId":247504,"journal":{"name":"Journal of Virology Research & Reports","volume":"224 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122857450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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