Lucien E. Weiss, Boris Ferdman, Onit Alalouf, Y. Shechtman
{"title":"超灵敏超临界角折射法无标记生物传感","authors":"Lucien E. Weiss, Boris Ferdman, Onit Alalouf, Y. Shechtman","doi":"10.1364/ISA.2019.ITH3B.2","DOIUrl":null,"url":null,"abstract":"By imaging the back focal plane of a fluorescence microscope, we demonstrate precise determination of a sample’s refractive index in a fluorophore-laden microfluidic device. We apply the technique to biosensing by detecting unlabeled bacteria.","PeriodicalId":123636,"journal":{"name":"Imaging and Applied Optics 2019 (COSI, IS, MATH, pcAOP)","volume":"80 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Label-Free Biosensing by Ultrasensitive Supercritical Angle Refractometry\",\"authors\":\"Lucien E. Weiss, Boris Ferdman, Onit Alalouf, Y. Shechtman\",\"doi\":\"10.1364/ISA.2019.ITH3B.2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"By imaging the back focal plane of a fluorescence microscope, we demonstrate precise determination of a sample’s refractive index in a fluorophore-laden microfluidic device. We apply the technique to biosensing by detecting unlabeled bacteria.\",\"PeriodicalId\":123636,\"journal\":{\"name\":\"Imaging and Applied Optics 2019 (COSI, IS, MATH, pcAOP)\",\"volume\":\"80 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-06-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Imaging and Applied Optics 2019 (COSI, IS, MATH, pcAOP)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1364/ISA.2019.ITH3B.2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Imaging and Applied Optics 2019 (COSI, IS, MATH, pcAOP)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1364/ISA.2019.ITH3B.2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Label-Free Biosensing by Ultrasensitive Supercritical Angle Refractometry
By imaging the back focal plane of a fluorescence microscope, we demonstrate precise determination of a sample’s refractive index in a fluorophore-laden microfluidic device. We apply the technique to biosensing by detecting unlabeled bacteria.
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