Chengjun Huang, J. Putzeys, J. Ye, G. Reekmans, K. Verhaegen, L. Lagae, K. Verstreken, G. Borghs
{"title":"多通道微流控芯片中基于局部表面等离子体共振的无标签生物传感器","authors":"Chengjun Huang, J. Putzeys, J. Ye, G. Reekmans, K. Verhaegen, L. Lagae, K. Verstreken, G. Borghs","doi":"10.1109/SAS.2009.4801774","DOIUrl":null,"url":null,"abstract":"A label-free biosensor based on localized surface plasmon resonance (LSPR) was developed. A multi-channel microfluidic chip was integrated with the sensor, providing referencing channel to minimize noise level and improving the throughput. With a CCD as a detector, a sensitivity of 10™4 RIU was demonstrated. The adsorption of S-layer protein was detected successfully by the sensor system.","PeriodicalId":410885,"journal":{"name":"2009 IEEE Sensors Applications Symposium","volume":"42 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2009-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Lable-free biosensor based on localized surface plasmon resonance in a multi-channel microfluidic chip\",\"authors\":\"Chengjun Huang, J. Putzeys, J. Ye, G. Reekmans, K. Verhaegen, L. Lagae, K. Verstreken, G. Borghs\",\"doi\":\"10.1109/SAS.2009.4801774\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A label-free biosensor based on localized surface plasmon resonance (LSPR) was developed. A multi-channel microfluidic chip was integrated with the sensor, providing referencing channel to minimize noise level and improving the throughput. With a CCD as a detector, a sensitivity of 10™4 RIU was demonstrated. The adsorption of S-layer protein was detected successfully by the sensor system.\",\"PeriodicalId\":410885,\"journal\":{\"name\":\"2009 IEEE Sensors Applications Symposium\",\"volume\":\"42 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-03-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2009 IEEE Sensors Applications Symposium\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/SAS.2009.4801774\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2009 IEEE Sensors Applications Symposium","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/SAS.2009.4801774","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Lable-free biosensor based on localized surface plasmon resonance in a multi-channel microfluidic chip
A label-free biosensor based on localized surface plasmon resonance (LSPR) was developed. A multi-channel microfluidic chip was integrated with the sensor, providing referencing channel to minimize noise level and improving the throughput. With a CCD as a detector, a sensitivity of 10™4 RIU was demonstrated. The adsorption of S-layer protein was detected successfully by the sensor system.