图兹拉州人群VNTR多态性eNOS基因的分子遗传分型

A. Avdić, N. Lojo-Kadrić, J. Ramic, L. Pojskic, Vesna Hadžiavdić
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引用次数: 0

摘要

本文报道了图兹拉州人群内皮型一氧化氮合酶(eNOS) VNTR基因多态性、遗传变异和分子分型的结果。根据eNOS基因型在调查对象中的分布分析,(b/b)基因型的频率最高,为73.0%。eNOS基因杂合(a/b)基因型的频率为24.0%,(a/a)基因型的频率为3.0%。这项研究产生了一个具有地方和全球意义的数据库,即将这些数据纳入现有的区域和欧洲遗传数据库。
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MOLECULAR-GENETIC TYPING OF VNTR POLYMORPHISM eNOS GENE IN HUMAN POPULATION OF TUZLA CANTON
The aim of the paper is to present the results of the VNTR gene polymorphism genetic variants molecular typing for endothelial nitric oxide synthase (eNOS) in human population of Tuzla Canton. Based on the analysis of the distribution of eNOS gene genotypes in the total sample of respondents, the highest frequency was recorded for the (b/b) genotype, which was 73.0%. For the heterozygous (a/b) genotype of the eNOS gene, a frequency of 24.0% was determined, and a frequency of 3.0% was recorded for the (a/a) genotype. The research resulted in a database of local and global significance, namely, the incorporation of these data into the existing regional and European genetic database.
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