Mina Aghaee, Mahnaz Abbaszadeh Alishahi, F. Manteghi
{"title":"Ba-MOF的抗菌活性","authors":"Mina Aghaee, Mahnaz Abbaszadeh Alishahi, F. Manteghi","doi":"10.3390/ecsoc-26-13725","DOIUrl":null,"url":null,"abstract":": The increasing tolerance and resistance of pathogens to conventional antibiotics is a global health issue, and there is a need to use effective and new substances. Metal–organic frameworks (MOFs) are highly functional materials with antimicrobial properties that come from their composition, structure, and high internal volume, which could be a source for antimicrobial guest molecules integrated into the pores. In addition, MOFs can contain more than one type of metal ion in the same structure. In this work, a metal–organic framework, [Ba(H 2 btec) · H 2 O] n , was synthesized by the deposition method using benzene-1,2,4,5-tetracarboxylic acid (H4btec) and Ba(NO 3 ) 2 . Characterization of the MOF was performed using Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD), Fourier Transform Infrared (FTIR) and x-ray fluorescence (XRF) alyses. The metal–organic framework was used against Gram-positive and Gram-negative bacteria including Keleb peneumonia , Staph coccus aureus , Staph sapropphyticus , and Esherichia coli .","PeriodicalId":255032,"journal":{"name":"The 26th International Electronic Conference on Synthetic Organic Chemistry","volume":"23 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Antimicrobial Activity of Ba-MOF\",\"authors\":\"Mina Aghaee, Mahnaz Abbaszadeh Alishahi, F. Manteghi\",\"doi\":\"10.3390/ecsoc-26-13725\",\"DOIUrl\":null,\"url\":null,\"abstract\":\": The increasing tolerance and resistance of pathogens to conventional antibiotics is a global health issue, and there is a need to use effective and new substances. Metal–organic frameworks (MOFs) are highly functional materials with antimicrobial properties that come from their composition, structure, and high internal volume, which could be a source for antimicrobial guest molecules integrated into the pores. In addition, MOFs can contain more than one type of metal ion in the same structure. In this work, a metal–organic framework, [Ba(H 2 btec) · H 2 O] n , was synthesized by the deposition method using benzene-1,2,4,5-tetracarboxylic acid (H4btec) and Ba(NO 3 ) 2 . Characterization of the MOF was performed using Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD), Fourier Transform Infrared (FTIR) and x-ray fluorescence (XRF) alyses. The metal–organic framework was used against Gram-positive and Gram-negative bacteria including Keleb peneumonia , Staph coccus aureus , Staph sapropphyticus , and Esherichia coli .\",\"PeriodicalId\":255032,\"journal\":{\"name\":\"The 26th International Electronic Conference on Synthetic Organic Chemistry\",\"volume\":\"23 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-11-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The 26th International Electronic Conference on Synthetic Organic Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3390/ecsoc-26-13725\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The 26th International Electronic Conference on Synthetic Organic Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/ecsoc-26-13725","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
: The increasing tolerance and resistance of pathogens to conventional antibiotics is a global health issue, and there is a need to use effective and new substances. Metal–organic frameworks (MOFs) are highly functional materials with antimicrobial properties that come from their composition, structure, and high internal volume, which could be a source for antimicrobial guest molecules integrated into the pores. In addition, MOFs can contain more than one type of metal ion in the same structure. In this work, a metal–organic framework, [Ba(H 2 btec) · H 2 O] n , was synthesized by the deposition method using benzene-1,2,4,5-tetracarboxylic acid (H4btec) and Ba(NO 3 ) 2 . Characterization of the MOF was performed using Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD), Fourier Transform Infrared (FTIR) and x-ray fluorescence (XRF) alyses. The metal–organic framework was used against Gram-positive and Gram-negative bacteria including Keleb peneumonia , Staph coccus aureus , Staph sapropphyticus , and Esherichia coli .