V. Pande, N. Mitra, S. Bagde, R. Srinivasan, P. Gayathri
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Filament organization of the bacterial actin MreB is dependent on the nucleotide state
Through the characterization of Spiroplasma MreB5, Pande et al. show that MreB5 exhibits a nucleotide-dependent allosteric effect on filament dynamics and membrane binding. The results highlight the conserved and distinct features of MreBs in shape determination, independent of peptidoglycan synthesis machinery.