某三级医院肺结核患者血清HIV感染的测定

D. Kinariwala
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摘要

人类免疫缺陷病毒(HIV)是结核病进展(TB)最有效的危险因素。由于艾滋病毒流行继续助长结核病流行,对结核病患者进行艾滋病毒监测已被认为是重要的。在同时感染艾滋病毒和结核病的人中,这种相互作用是双向的和协同的。本研究的目的是确定在三级护理医院肺结核患者的血清艾滋病毒感染的患病率。方法:对4500例确诊结核病患者进行了为期一年的研究,并按照国家艾滋病控制组织(NACO)的指导方针检测了HIV抗体。结果显示,在接受筛查的4500名患者中,有244人(5.42%)呈HIV阳性。男女比例为2.34(171/73),35 ~ 50岁人群共感染发生率最高。结论:目前的研究发现结核病患者的HIV血清阳性率为5.42%。结核病患者感染艾滋病毒的早期诊断将有助于更快地获得护理和治疗,包括抗逆转录病毒治疗。这将减少艾滋病毒-结核病合并感染患者的死亡和患病人数。
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Determining the Seroprevalence of HIV Infection among Tuberculosis Patients in a Tertiary Care Hospital
Introduction: The Human Immunodeficiency Virus (HIV) is the most potent risk factor for Tuberculosis progression (TB). Surveillance of HIV among & TB patients has been recognized to be important as the HIV epidemic continues to fuel TB epidemic. In those who are infected with both HIV and TB, the interaction is bidirectional and synergistic. The purpose of this study was to determine the seroprevalence of HIV infection among patients with tuberculosis in a tertiary care hospital. Method: A one-year study of 4500 confirmed tuberculosis patients was conducted, and HIV antibodies were tested in accordance with National AIDS Control Organisation (NACO) guidelines. The results showed that 244 (5.42 percent) of the 4500 patients screened were HIV positive. The male to female ratio was 2.34 (171/73), and the prevalence of co-infection was highest among those aged 35 to 50 years. Conclusion: The current study found 5.42 percent HIV seroprevalence in tuberculosis patients. Early diagnosis of HIV infection in tuberculosis patients will allow for quicker access to care and treatment, including antiretroviral therapy (ART).  This will reduce the number of deaths and illnesses among HIV-TB co-infected patients.
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