{"title":"肥厚性心肌病异常Q波发生的心肌各向异性:模拟研究","authors":"D. Wei, N. Miyamoto, S. Mashima","doi":"10.1109/ICBEM.1998.666456","DOIUrl":null,"url":null,"abstract":"Computer simulation with a whole-heart model was conducted to study genesis of abnormal Q waves in hypertrophic cardiomyopathy (HCM). The anatomic feature of HCM was modeled based on clinical echocardiogram images. Possible changes in anisotropy as well as in other electrophysiologic properties in hypertrophic tissue were simulated based on pathologic findings. Simulated ECGs showing the main features of HCM were obtained by assuming isotropic fiber orientation in hypertrophic tissue and by changing other properties from normal values. This study suggests a possible mechanism to account for abnormal Q waves in HCM.","PeriodicalId":213764,"journal":{"name":"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1998-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Myocardial anisotropy in genesis of abnormal Q waves in hypertrophic cardiomyopathy: a simulation study\",\"authors\":\"D. Wei, N. Miyamoto, S. Mashima\",\"doi\":\"10.1109/ICBEM.1998.666456\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Computer simulation with a whole-heart model was conducted to study genesis of abnormal Q waves in hypertrophic cardiomyopathy (HCM). The anatomic feature of HCM was modeled based on clinical echocardiogram images. Possible changes in anisotropy as well as in other electrophysiologic properties in hypertrophic tissue were simulated based on pathologic findings. Simulated ECGs showing the main features of HCM were obtained by assuming isotropic fiber orientation in hypertrophic tissue and by changing other properties from normal values. This study suggests a possible mechanism to account for abnormal Q waves in HCM.\",\"PeriodicalId\":213764,\"journal\":{\"name\":\"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)\",\"volume\":\"49 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1998-02-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICBEM.1998.666456\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICBEM.1998.666456","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Myocardial anisotropy in genesis of abnormal Q waves in hypertrophic cardiomyopathy: a simulation study
Computer simulation with a whole-heart model was conducted to study genesis of abnormal Q waves in hypertrophic cardiomyopathy (HCM). The anatomic feature of HCM was modeled based on clinical echocardiogram images. Possible changes in anisotropy as well as in other electrophysiologic properties in hypertrophic tissue were simulated based on pathologic findings. Simulated ECGs showing the main features of HCM were obtained by assuming isotropic fiber orientation in hypertrophic tissue and by changing other properties from normal values. This study suggests a possible mechanism to account for abnormal Q waves in HCM.
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