公共卫生策略的并行低差异参数扫描

Sudheer Chunduri, Meysam Ghaffari, M. S. Lahijani, A. Srinivasan, S. Namilae
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引用次数: 11

摘要

数值模拟用于分析不同公共政策选择在限制传染病传播方面的有效性。在实践中,由于固有的不确定性,特别是在流行病的早期阶段,通常无法准确预测其影响。一种选择是参数化不确定性的来源,并进行参数扫描,以确定其在各种可能情况下的鲁棒性。自推进实体动力学(Self - Propelled Entity Dynamics, SPED)模型利用该方法成功地分析了不同航线登机和下机过程的鲁棒性。然而,这种方法所花费的时间太长,无法回答决策会议过程中提出的问题。在本文中,我们使用了一种改进的方法,即预先计算乘客运动的模拟,仅实时执行特定疾病的分析。本文的一个新颖贡献在于在参数扫描中使用低差异序列(LDS),并证明它可以使分析时间比传统的基于格的参数扫描减少一到三个数量级。然而,与传统方法相比,它的并行性受到更大的负载不平衡的影响。我们对此进行了研究,并将其与LDS的数论性质联系起来。然后我们提出解决这个问题的方法。我们的方法和分析也适用于其他参数扫描问题。本文的主要贡献在于低差异参数扫描的新方法,并探索其并行化挑战的解决方案,在一个重要的公共卫生应用的背景下进行评估。
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Parallel Low Discrepancy Parameter Sweep for Public Health Policy
Numerical simulations are used to analyze the effectiveness of alternate public policy choices in limiting the spread of infections. In practice, it is usually not feasible to predict their precise impacts due to inherent uncertainties, especially at the early stages of an epidemic. One option is to parameterize the sources of uncertainty and carry out a parameter sweep to identify their robustness under a variety of possible scenarios. The Self Propelled Entity Dynamics (SPED) model has used this approach successfully to analyze the robustness of different airline boarding and deplaning procedures. However, the time taken by this approach is too large to answer questions raised during the course of a decision meeting. In this paper, we use a modified approach that pre-computes simulations of passenger movement, performing only the disease-specific analysis in real time. A novel contribution of this paper lies in using a low discrepancy sequence (LDS) in the parameter sweep, and demonstrating that it can lead to a reduction in analysis time by one to three orders of magnitude over the conventional lattice-based parameter sweep. However, its parallelization suffers from greater load imbalance than the conventional approach. We examine this and relate it to number-theoretic properties of the LDS. We then propose solutions to this problem. Our approach and analysis are applicable to other parameter sweep problems too. The primary contributions of this paper lie in the new approach of low discrepancy parameter sweep and in exploring solutions to challenges in its parallelization, evaluated in the context of an important public health application.
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